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Neurophysiological and behavioral measures of pain during neonatal hip examination
Örebro University, School of Medical Sciences. Department of Paediatrics. (PEARL - Pain in Early Life)ORCID iD: 0000-0003-3762-7627
Örebro University, School of Health Sciences. Department of Paediatrics. (PEARL - Pain in Early Life)ORCID iD: 0000-0002-5582-6147
Örebro University, School of Medical Sciences. Örebro University Hospital. Department of Paediatrics.ORCID iD: 0000-0003-0531-6189
Örebro University, School of Health Sciences. Department of Paediatrics. (PEARL - Pain in Early Life)ORCID iD: 0000-0002-5996-2584
2019 (English)In: Paediatric and Neonatal Pain, ISSN 2379-5824, Vol. 1, no 1, p. 15-20Article in journal (Refereed) Published
Abstract [en]

Introduction: The aim of this study was to test the hypothesis that neonatal hip ex ‐amination causes pain in newborns. Pain assessment using instruments such as the Premature Infant Pain Profile‐Revised (PIPP‐R) scale is recommended, but recently physiological and neurophysiological measures, for example, near‐infrared spectros‐copy (NIRS) and galvanic skin response (GSR), have been used as well.

Methods: Heart auscultation and hip examination were performed, and the response of the newborn was registered by NIRS optodes, GSR electrodes, and a pulse oxime‐ter probe attached to the infant. The face of the newborn was filmed. Heart ausculta‐tion was used as a nonpainful reference.

Results: The pain scores for hip examination were higher than for the heart ausculta‐tion. Near‐infrared spectroscopy showed a significant higher increase from baseline in oxygenated hemoglobin (HbO2) on both sides of the cortex at hip examination compared with at heart auscultation (P = .011 and P= .017). Mean PIPP‐R scores for the hip examination compared with heart auscultation increased from 3.0 to 8.1 (P = .000). The GSR analyses of hip examination compared with heart auscultation showed a significant increase in area under small peaks during the hip examination (P = .016), however, not when measured in peaks per second (P = .104). Interrater reliability was calculated for the NIRS interpretations, with an intraclass correlation coefficient (ICC) range of 0.93‐1.0 (P = .000).

Discussion: Pain in newborns can have negative consequences, and pain prevention and treatment are therefore important. We conclude that neonatal hip examinations are painful and that the pain should be treated, for example, with oral sweet solution. This is a change from present routines during neonatal hip examination and is hoped to lead to a change in national guidelines.

Place, publisher, year, edition, pages
John Wiley & Sons, 2019. Vol. 1, no 1, p. 15-20
Keywords [en]
Neonatal hip examination, neonatal pain
National Category
Pediatrics Nursing
Research subject
Pediatrics; Caring Sciences w. Medical Focus
Identifiers
URN: urn:nbn:se:oru:diva-76413DOI: 10.1002/pne2.12006OAI: oai:DiVA.org:oru-76413DiVA, id: diva2:1351320
Available from: 2019-09-14 Created: 2019-09-14 Last updated: 2021-02-01Bibliographically approved
In thesis
1. Routine procedures in the care of the full-term newborn
Open this publication in new window or tab >>Routine procedures in the care of the full-term newborn
2021 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis presents four studies on routine procedures used in the care of the full-term newborn. The overall aim of the thesis was to study the effects of these routines and endeavour to find ways to improve them.

Study I, an observational study, included 28 healthy newborns, assessing pain during neonatal hip examination. Pain was assessed using Premature Infant Pain Profile-Revised (PIPP-R), near infrared spectroscopy (NIRS) and galvanic skin response (GSR). The results showed that the pain scores and NIRS and GSR readings were significantly higher for hip examination than for the heart auscultation indicating that neonatal hip examinations are painful.

Study II was as a double blind, randomized controlled trial (99 patients included) evaluating whether oral sweet solution has a pain relieving effect during neonatal hip examination. Total crying time, crying time during the hip examination, ALPS-Neo and VAS (when assessed by the physician) were all significantly decreased in the group of infants receiving glucose, the conclusion drawn from this is that oral sweet solution seems to have a painrelieving effect during neonatal hip examination.

Study III and IV were based on a multicenter randomized controlled study, where 147 patients from 6 hospitals were included. Study III evaluated whether home phototherapy could be a feasible and safe alternative to in hospital phototherapy for term newborns. The results showed that home phototherapy could be a safe alternative to inpatient phototherapy for otherwise healthy newborn infants with hyperbilirubinemia if daily check-ups and 24/7 telephone support can be provided.

Study IV, examined parent’s experiences of home phototherapy (n=15) using a qualitative design. The study showed that the overall experience was positive and that parents expressed a sense of feeling safe with managing the treatment at home. They also felt that the ability to provide phototherapy at home helped them to adapt to everyday life and enhanced their positive experience of parenthood.

Place, publisher, year, edition, pages
Örebro: Örebro University, 2021. p. 75
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 228
Keywords
Newborn, pain, neonatal hyperbilirubinemia, home phototherapy, neonatal hip examination, oral sweet solution, pain assessment
National Category
General Practice
Identifiers
urn:nbn:se:oru:diva-87880 (URN)978-91-7529-367-7 (ISBN)
Public defence
2021-02-12, Örebro universitet, Campus USÖ, hörsal C1, Södra Grev Rosengatan 32, Örebro, 10:00 (Swedish)
Opponent
Supervisors
Available from: 2020-12-08 Created: 2020-12-08 Last updated: 2022-03-28Bibliographically approved

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Pettersson, MiriamOlsson, EmmaOhlin, Andreas

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