Detecting chemical compounds using electronic noses is important in many gas sensing related applications. Existing gas detection methods typically use prior knowledge of the target analytes. However, in some scenarios, the analytes to be detected are not fully known in advance, and preparing a dedicated model is not possible. To address this issue, we propose a gas detection approach using an ensemble of one-class classifiers. The proposed approach is initialized by learning a Mahalanobis-based and a Gaussian based model using clean air only. During the sampling process, the presence of chemicals is detected by the initialized system, which allows to learn a one-class nearest neighbourhood model without supervision. From then on the gas detection considers the predictions of the three one-class models. The proposed approach is validated with real-world experiments, in which a mobile robot equipped with an e-nose was remotely controlled to interact with different chemical analytes in an open environment.