ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissectionDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Heart Centre, Tampere University Hospital, Tampere, Finland.
Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden.
Heart Centre, Turku University Hospital and University of Turku, Turku, Finland.
Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.
Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.
Section of Cardiac Surgery, Yale University School of Medicine, New Haven, CT, USA.
Section of Cardiac Surgery, Yale University School of Medicine, New Haven, CT, USA; Department of Cardiothoracic Surgery, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Department of Cardiothoracic Surgery, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.
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2020 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 54, no 2, p. 124-129Article in journal (Refereed) Published
Abstract [en]
Objectives: To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD).
Design: A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality.
Results: There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7-43.4)% vs 39.0 (95% CI 39.0-39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups.
Conclusions: In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.
Place, publisher, year, edition, pages
Taylor & Francis, 2020. Vol. 54, no 2, p. 124-129
Keywords [en]
Aorta, NORCAAD, aneurysm, blood group, dissection
National Category
Surgery Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:oru:diva-77617DOI: 10.1080/14017431.2019.1679387ISI: 000491657800001PubMedID: 31642332Scopus ID: 2-s2.0-85074484296OAI: oai:DiVA.org:oru-77617DiVA, id: diva2:1365509
Note
Funding Agencies:
University of Iceland
Landspitali Research Fund in Reykjavik, Iceland
Mats Kleberg Foundation, Stockholm, Sweden
2019-10-252019-10-252024-01-02Bibliographically approved