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Diagnosis and management of microscopic colitis
Örebro University, School of Health and Medical Sciences.
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2008 (English)In: World Journal of Gastroenterology, ISSN 1007-9327, E-ISSN 2219-2840, Vol. 14, no 48, p. 7280-7288Article in journal (Other academic) Published
Abstract [en]

Microscopic colitis, comprising collagenous and lymphocytic colitis, is characterized clinically by chronic watery diarrhea, and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscopic examination. The annual incidence of each disorder is 4-6/100,000 inhabitants, with a peak incidence in 60-70-year-old individuals and a noticeable female predominance for collagenous colitis. The etiology is unknown. Chronic diarrhea, abdominal pain, weight loss, fatigue and fecal incontinence are common symptoms, which impair the health-related quality of life of the patient. There is an association with other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented short-term treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.

Place, publisher, year, edition, pages
Beijing: WJG Press , 2008. Vol. 14, no 48, p. 7280-7288
National Category
Medical and Health Sciences Clinical Medicine Gastroenterology and Hepatology
Research subject
Internal Medicine
Identifiers
URN: urn:nbn:se:oru:diva-3799DOI: 10.3748/wjg.14.7280PubMedID: 19109861OAI: oai:DiVA.org:oru-3799DiVA, id: diva2:138097
Available from: 2009-01-07 Created: 2009-01-07 Last updated: 2017-12-14Bibliographically approved

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Tysk, CurtBohr, JohanNyhlin, NilsWickbom, Anna

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
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Language
  • de-DE
  • en-GB
  • en-US
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  • Other locale
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