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Bone formation after implantation of autolysed antigen extracted allogeneic bone in ovariectomized rabbits
Örebro University, Department of Health Sciences. Örebro University, Department of Clinical Medicine.
2003 (English)In: International Journal of Oral and Maxillofacial Surgery, ISSN 0901-5027, E-ISSN 1399-0020, Vol. 32, no 6, p. 628-632Article in journal (Refereed) Published
Abstract [en]

This study was undertaken to evaluate the bone formation response to AAA bone in healthy and oestrogen deficient animals. Seventeen young healthy New Zealand female rabbits were used. Nine rabbits were subjected to ovariectomy and the remaining eight were sham-operated. Four weeks after ovariectomy standardized round cavities, 5 mm in diameter, were made medially in the cortical part of each proximal tibia. To half of the cavities autolysed antigen-extracted allogeneic AAA bone granules were added. After another 8 weeks the animals were sacrificed and sections of the tibial experimental areas were obtained. These were studied in light microscopy and the bone and non-bone areas were measured with computer support.

The study showed that the addition of a bone inductive substance such as AAA bone enhances bone formation also in oestrogen deficient animals.

Place, publisher, year, edition, pages
2003. Vol. 32, no 6, p. 628-632
National Category
Medical and Health Sciences
Research subject
Medicine
Identifiers
URN: urn:nbn:se:oru:diva-4343DOI: 10.1054/ijom.2003.0428OAI: oai:DiVA.org:oru-4343DiVA, id: diva2:138642
Available from: 2008-02-19 Created: 2008-02-19 Last updated: 2017-12-14Bibliographically approved

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Johansson, Carina B.

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