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Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption
Örebro University, Department of Clinical Medicine.
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2007 (English)In: Journal of biomedical materials research. Part B, Applied biomaterials, ISSN 1552-4973, Vol. 83B, no 1, p. 9-15Article in journal (Refereed) Published
Abstract [en]

Bonit is claimed to be a resorbable electrochemically deposited calcium phosphate coating consisting mainly of brushite, which is a hydroxyapatite precursor. This study involved a comparison of Ti6Al4V screw-shaped implants with and without a 15 +/- 5 microm Bonit coating in rabbit tibia and femur, after 6 and 12 weeks of insertion. The biomechanical removal torque test showed significantly increased values for the coated implants after 12 weeks (p < 0.05) but not after 6 weeks of integration. Higher bone-implant contact was found for the coated implants in the tibia after 6 weeks and for both tibial and femoral screws after 12 weeks (p < 0.05). There was no difference in the inflammatory reaction around the implants, and possible grains of the coating could be detected after 6 weeks, but not after 12 weeks of follow-up. This unloaded short-term study has shown promising results for the easily applicable and resorbable coat (Bonit) compared to uncoated titanium-alloy implants.

Place, publisher, year, edition, pages
2007. Vol. 83B, no 1, p. 9-15
National Category
Medical and Health Sciences Surgery Surgery Surgery
Research subject
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-4372DOI: 10.1002/jbm.b.30762OAI: oai:DiVA.org:oru-4372DiVA, id: diva2:138671
Available from: 2008-02-19 Created: 2008-02-19 Last updated: 2017-10-18Bibliographically approved

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Johansson, Carina B.

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