The chapter aims to discuss the concept of social skills and relating concepts like social competence and socio-emotional learning and the status of these concept in Early Childhood Education and Care, ECEC internationally and within the Swedish preschool context in special. With a theoretical stance in systems theory and bio-ecological models, recent research on the impact of social skills on educational development and children’s health will be explored and discussed in the chapter. The impact of intrapersonal factors such as resilience as well as interpersonal relations and factors on different systems levels that reciprocally influence the everyday functioning of the child are presented. The aim of the chapter is also to share a general discussion of some of the many existing educational programs for teachers and/or parents aiming at strengthening the social skills of children, with a specific focus on their implications for the practice. The chapter ends with a discussion of how practitioners working with preschool children can adopt a holistic view of the capabilities of the child, thus strengthening the social skills and promoting educational development and health.