oru.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Skeletal muscle telomere length is not impaired in healthy physically active old women and men
Örebro University, School of Health and Medical Sciences. (Muscle & Exercise Physiology Research Group , RISPA)ORCID iD: 0000-0002-8071-4745
Department of Rehabilitation, Lund University Hospital, Lund, Sweden.
Örebro University, School of Health and Medical Sciences. (Muscle & Exercise Physiology Research Group , RISPA)ORCID iD: 0000-0002-9831-0896
2008 (English)In: Muscle and Nerve, ISSN 0148-639X, E-ISSN 1097-4598, Vol. 37, no 4, p. 467-472Article in journal (Refereed) Published
Abstract [en]

We have previously shown that the number of satellite cells is lower in old than young men and women. The aim of this study was to further explore the effects of aging on the regenerative potential of skeletal muscle in 16 young and 26 old men and women with comparable physical activity level (young, 25 +/- 4 years; old, 75 +/- 4 years). Mean and minimum telomere lengths were determined using Southern blot analyses on biopsies obtained from the tibialis anterior muscle. There were no significant age or gender effects on mean and minimal telomeric lengths, suggesting that the replicative potential in the remaining satellite cells in the tibialis anterior muscle is not impaired with increasing age and the existence of in vivo regulatory mechanisms allowing the maintenance of telomere length. These results imply that moderate physical activity regularly performed by old subjects is not associated with accelerated telomere loss.

Place, publisher, year, edition, pages
2008. Vol. 37, no 4, p. 467-472
Keywords [en]
Adult, Aged, Aged; 80 and over, Aging/*physiology, Biopsy, Female, Humans, Male, Motor Activity/*physiology, Muscle; Skeletal/cytology/*physiology, Musculoskeletal Equilibrium/physiology, Satellite Cells; Skeletal Muscle/cytology, Telomere/*physiology, Walking/physiology
National Category
Physiology Medical and Health Sciences Social Sciences Interdisciplinary Sport and Fitness Sciences
Research subject
Sports Science
Identifiers
URN: urn:nbn:se:oru:diva-4609DOI: 10.1002/mus.20964PubMedID: 18236464OAI: oai:DiVA.org:oru-4609DiVA, id: diva2:138908
Available from: 2008-09-25 Created: 2008-09-25 Last updated: 2018-01-13Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=18236464&dopt=Citation

Authority records BETA

Ponsot, ElodieKadi, Fawzi

Search in DiVA

By author/editor
Ponsot, ElodieKadi, Fawzi
By organisation
School of Health and Medical Sciences
In the same journal
Muscle and Nerve
PhysiologyMedical and Health SciencesSocial Sciences InterdisciplinarySport and Fitness Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 326 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf