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Fasting capillary glucose as a screening test for gestational diabetes mellitus
Örebro University Hospital. Department of Obstetrics and Gynaecology .ORCID iD: 0000-0002-2691-7525
Örebro University Hospital. Department of Obstetrics and Gynaecology .
Örebro University Hospital. Department of Obstetrics and Gynaecology and Department of Clinical Medicine, Section of Obstetrics and Gynecology.
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden.
2006 (English)In: BJOG: an International Journal of Obstetrics and Gynaecology, ISSN 1470-0328, Vol. 113, no 9, p. 1067-71Article in journal (Refereed) Published
Abstract [en]

Objective: To evaluate fasting capillary glucose as a screening test for gestational diabetes mellitus (GDM) compared with traditional risk factors and repeated random capillary glucose measurements.

Design: Cross-sectional, population-based study.

Setting: Maternal Health Care Clinics in Orebro County, Sweden.

Population: An unselected population of women without diabetes.

Methods: Fasting capillary glucose levels were measured at gestational weeks 28-32. Random capillary glucose levels were measured four to six times during pregnancy. Traditional risk factors for GDM were registered. GDM was diagnosed using a 75-g oral glucose tolerance test.

Main outcome measures: Sensitivity, specificity, likelihood ratios.

Results: In 55 of 3616 women participating in the study, GDM was diagnosed before 34 weeks of gestation. For fasting capillary glucose cutoff values between 4.0 and 5.0 mmol/l, sensitivity was in the range between 87 and 47% and specificity between 51 and 96%. Using a combined screening model of traditional risk factors with fasting capillary glucose at various cutoff values increased the sensitivity only slightly compared with using fasting capillary glucose alone.

Conclusion: In this Swedish, unselected, low-risk population, fasting capillary glucose measurements were found to be an acceptable and useful screening test for GDM.

Place, publisher, year, edition, pages
Oxford: Blackwell Publishing, 2006. Vol. 113, no 9, p. 1067-71
Keywords [en]
fasting capillary glucose; gestational diabetes mellitus; screening; sensitivity; specificity
National Category
Obstetrics, Gynecology and Reproductive Medicine
Research subject
Obstetrics and Gynaecology
Identifiers
URN: urn:nbn:se:oru:diva-4668DOI: 10.1111/j.1471-0528.2006.01032.xISI: 000240030600015PubMedID: 16956338Scopus ID: 2-s2.0-33748161345OAI: oai:DiVA.org:oru-4668DiVA, id: diva2:138967
Note

Comment in: BJOG. 2007 Feb;114(2):237-8; author reply 238-9. BJOG. 2007 Mar;114(3):372; author reply 373.

Available from: 2008-11-11 Created: 2008-11-11 Last updated: 2017-10-18Bibliographically approved
In thesis
1. Gestational diabetes mellitus in Sweden: screening, outcomes, and consequences
Open this publication in new window or tab >>Gestational diabetes mellitus in Sweden: screening, outcomes, and consequences
2012 (English)Doctoral thesis, comprehensive summary (Other academic)
Place, publisher, year, edition, pages
Örebro: Örebro universitet, 2012. p. 68
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 65
Keywords
Gestational diabetes mellitus, fasting blood glucose, screening, neonatal and obstetric outcomes, ethnicity, cardiovascular disease
National Category
Surgery
Research subject
Surgery
Identifiers
urn:nbn:se:oru:diva-20621 (URN)978-91-7668-847-2 (ISBN)
Public defence
2012-02-17, Wilandersalen, M-huset, Universitetssjukhuset, Örebro, 09:00 (English)
Opponent
Supervisors
Available from: 2011-12-22 Created: 2011-12-22 Last updated: 2019-04-24Bibliographically approved

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Fadl, HelenaÖstlund, IngridNilsson, Kerstin

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