Pharmacotherapy in women
2017 (English)In: Manual of Gynecardiology: Female-Specific Cardiology / [ed] Maas, Angela H.E.M.; Bairey Merz, C. Noel., Springer, 2017Chapter in book (Other academic)
Abstract [en]
Pharmacokinetic properties such as absorption, distribution, metabolism, and elimination of drugs often differ between men and women and change over lifetime. Women experience more adverse events and side-effects of medications than men. Hormonal changes during the menstrual cycle usually have limited effect on the pharmacokinetics of drugs, except for drugs that interfere with QT-interval. It is debated whether there is a systematic difference in compliance to medication in women compared to men. Drug interactions and drug safety during pregnancy are discussed.
Place, publisher, year, edition, pages
Springer, 2017.
Keywords [en]
Anti-arrhythmic drugs, Beta-blockers, CYP3A4 inhibitors, Drug interactions, Drug safety, Estrogen, Glomerular filtration rate (GFR), Medication adherence, Menopause, Pharmacodynamics, Pharmacokinetics, Pregnancy, QT-interval, Sex-hormones, Side-effects, Statins, Torsade de Pointes (TdP)
National Category
Medical and Health Sciences Neurosciences
Identifiers
URN: urn:nbn:se:oru:diva-81183DOI: 10.1007/978-3-319-54960-6_14ISBN: 978-3-319-54959-0 (print)ISBN: 978-3-319-54960-6 (electronic)OAI: oai:DiVA.org:oru-81183DiVA, id: diva2:1424334
2020-04-172020-04-172024-01-02Bibliographically approved