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The general factor of psychopathology: a comparison with the general factor of intelligence with respect to magnitude and predictive validity
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-6851-3297
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Depart- ment of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.
4 Center for Psychiatry Research, Department of Women’s and Children’s Health, Stock- holm Health Care Services & Karolinska Institutet, Stockholm, Sweden.
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2020 (English)In: World Psychiatry, ISSN 1723-8617, E-ISSN 2051-5545, Vol. 19, no 2, p. 206-213Article, review/survey (Refereed) Published
Abstract [en]

In recent years, there has been a surge of interest in the general factor of psychopathology (“p”), which is intended to summarize broad psychiat­ric comorbidity into a single index. In this study, rather than attempting to validate this model using statistical techniques, we compared the magnitude (as indicated by the variance explained in the respective indicators) and the predictive validity of the “p” factor with those of the gen­eral factor of intelligence (“g”). To compare the magnitude, for “g”, we analyzed fifteen Wechsler Adult Intelligence Scale subtests (N=1,200). For “p”, we analyzed fourteen psychiatric diagnoses in Swedish adults (N=909,699), eight self- and parent-rated psychopathology scales in Swedish adolescents (N=2,069), and sixteen parent-rated psychopathology scales in Swedish children (N=14,589). To compare the predictive validity, we analyzed Swedish male military conscripts (N=414,595, mean age: 18.3 years) with measures on both “g” and “p” (derived from eight psychiatric diagnoses). We then examined their unique associations with three intelligence-related outcomes (annual income, highest education, and university entrance exam scores), and sixteen adverse outcomes (e.g., suicidal behavior, psychotropic medication prescription, and criminality) retrieved from registers (mean age at follow-up = 29.2 years). Results indicated that the magnitudes of “g” and “p” were very similar. Controlling for “p”, “g” significantly predicted later education (standardized beta, β=0.38, SE=0.01) and university entrance exam scores (β=0.48, SE=0.01). Controlling for “g”, “p” significantly predicted all adverse outcomes (mean β=0.32; range: 0.15 to 0.47). These findings support the notion that psychopathology indicators can be combined into a single score, similar to how intelligence subtests are combined into a general intelligence score. This “p” score might supplement specific diagnoses when formulating a management plan and predicting prognosis.

Place, publisher, year, edition, pages
Masson SpA , 2020. Vol. 19, no 2, p. 206-213
Keywords [en]
Clinical utility, g factor, general factor of intelligence, General factor of psychopathology, magnitude, mental disorders, p factor, predictive validity, psychiatric co­morbidity
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-81974DOI: 10.1002/wps.20763ISI: 000531494700020PubMedID: 28026869Scopus ID: 2-s2.0-85084482021OAI: oai:DiVA.org:oru-81974DiVA, id: diva2:1431550
Funder
Swedish Research Council, 2017-01358
Note

Funding Agency:

Swedish Research Council through the Swedish Initiative for Research on Microdata in the Social and Medical Sciences (SIMSAM)  340-2013-5867

Available from: 2020-05-22 Created: 2020-05-22 Last updated: 2020-05-29Bibliographically approved

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