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NIEHS/FDA CLARITY-BPA research program update
Division of Extramural Research and Training, National Institute of Environmental Health Sciences, USA.
Division of the National Toxicology Program, National Institute of Environmental Health Sciences, USA.
Division of the National Toxicology Program, National Institute of Environmental Health Sciences, USA.
Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, USA.
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2015 (English)In: Reproductive Toxicology, ISSN 0890-6238, E-ISSN 1873-1708, Vol. 58, p. 33-44Article, review/survey (Refereed) Published
Abstract [en]

Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S. Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program.

Place, publisher, year, edition, pages
Elsevier, 2015. Vol. 58, p. 33-44
Keywords [en]
Bisphenol A, CLARITY-BPA, Consortium, Endocrine disruptors, FDA, NIEHS, NTP
National Category
Environmental Sciences Pharmacology and Toxicology
Research subject
Enviromental Science
Identifiers
URN: urn:nbn:se:oru:diva-83766DOI: 10.1016/j.reprotox.2015.07.075ISI: 000367559600005PubMedID: 26232693Scopus ID: 2-s2.0-84939812084OAI: oai:DiVA.org:oru-83766DiVA, id: diva2:1448174
Note

Funding Agency:

National Toxicology Program

Food and Drug Administration

National Institute of Environmental Health Sciences/National Institutes of Health, Grant Number: FDA IAG: 224-12-0003, NIEHS IAG: AES12013

Available from: 2020-06-26 Created: 2020-06-26 Last updated: 2021-02-26Bibliographically approved

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Zoeller, R. Thomas

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