To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Higher body mass index at ages 16 to 20 years is associated with increased risk of a multiple sclerosis diagnosis in subsequent adulthood among men
Örebro University, School of Medical Sciences. Clinical Epidemiology and Biostatistics.ORCID iD: 0000-0003-3718-4715
Örebro University, School of Medical Sciences. Clinical Epidemiology and Biostatistics.ORCID iD: 0000-0002-2088-0530
Örebro University, School of Medical Sciences. Örebro University Hospital. Clinical Epidemiology and Biostatistics.ORCID iD: 0000-0002-3720-1274
Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID iD: 0000-0002-9811-908X
Show others and affiliations
2021 (English)In: Multiple Sclerosis Journal, ISSN 1352-4585, E-ISSN 1477-0970, Vol. 27, no 1, p. 147-150Article in journal (Refereed) Published
Abstract [en]

Background: Evidence for the association between body mass index (BMI) and multiple sclerosis (MS) among men remains mixed.

Objective and methods: Swedish military conscription and other registers identified MS after age of 20 years and BMI at ages 16-20 years (N = 744,548).

Results: Each unit (kg/m(2)) BMI increase was associated with greater MS risk (hazard ratio and 95% confidence interval = 1.034, 1.016-1.053), independent of physical fitness (1.021, 1.001-1.042). Categorised, overweight and obesity were associated with statistically significant raised MS risk compared to normal weight, but not after adjustment for physical fitness.

Conclusion: MS risk rises with increasing BMI, across the entire BMI range.

Place, publisher, year, edition, pages
Sage Publications, 2021. Vol. 27, no 1, p. 147-150
Keywords [en]
Obesity, underweight, body mass index, multiple sclerosis, men, adolescence
National Category
Neurology
Identifiers
URN: urn:nbn:se:oru:diva-84506DOI: 10.1177/1352458520928061ISI: 000539062700001PubMedID: 32507076Scopus ID: 2-s2.0-85086112570OAI: oai:DiVA.org:oru-84506DiVA, id: diva2:1457889
Funder
Swedish Research CouncilThe Swedish Brain Foundation
Note

Funding Agencies:

Economic & Social Research Council (ESRC) RES-596-28-0001 ES/JO19119/1

Nyckelfonden 

Available from: 2020-08-13 Created: 2020-08-13 Last updated: 2022-10-17Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Xu, YinHiyoshi, AyakoBrand, JudithMontgomery, Scott

Search in DiVA

By author/editor
Xu, YinHiyoshi, AyakoBrand, JudithSmith, Kelsi A.Montgomery, Scott
By organisation
School of Medical SciencesÖrebro University Hospital
In the same journal
Multiple Sclerosis Journal
Neurology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 455 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf