To Örebro University

oru.seÖrebro University Publications
Planned maintenance
A system upgrade is planned for 10/12-2024, at 12:00-13:00. During this time DiVA will be unavailable.
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Engineered nanoselenium supplemented fish diet: toxicity comparison with ionic selenium and stability against particle dissolution, aggregation and release
Institute of Environmental Sciences (CML), Van Steenis Building, Leiden University, Leiden, The Netherlands .
Örebro University, School of Science and Technology. Biology, Örebro Life Science Center, School of Science and Technology, Örebro University, Örebro, Sweden; Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, University of South Bohemia in Ceske Budejovice, Vodňany, Czech Republic .ORCID iD: 0000-0002-9001-5809
Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic .
Institute of Environmental Sciences (CML), Van Steenis Building, Leiden University, Leiden, The Netherlands; Leiden University College The Hague, Leiden University, The Hague, The Netherlands .
Show others and affiliations
2020 (English)In: Environmental Science: Nano, ISSN 2051-8153, Vol. 7, no 8, p. 2325-2336Article in journal (Refereed) Published
Abstract [en]

Transformation of nutrients to their nano-form, such as selenium (Se) engineered nanonutrients (Se-ENNs), is expected to enhance the absorption of the nutrients into fish and increase the efficiency of the feed. However, dissolution, aggregation, and release of ENNs from the feed matrix may decrease the efficiency of the Se-ENNs. In this study, we provided fish feed supplemented with Se-ENNs which do not aggregate or dissolve and the particles are also not released from the feed matrix. As a proof of principle, we compared the toxicity of a diet containing Se-ENNs of two different sizes (60 nm and 120 nm) with diets containing ionic Se. The adverse effects were measured by monitoring the survival rate, acetylcholinesterase (AChE) levels and swimming behavior of zebrafish over 21 days of feeding with either the Se-ENNs or ionic Se supplemented fish diets. The number size distribution of the 60 nm Se-ENNs in the diet was similar to that in MilliQ water, while the size distribution of the 120 nm Se-ENNs in the diet was slightly wider. Ion and particle release from Se-ENNs containing diets in the exposure media was not observed, indicating the stability of the particles in the feed matrices. To determine toxicity, zebrafish (Danio rerio) were nourished using a control diet (without Se and Se-ENNs), Se (sodium selenite) containing diets (with 2.4 or 240 mg Se per kg feed) and Se-ENNs containing diets (with 2.4 or 240 mg Se-ENNs of 60 or 120 nm per kg feed) for 21 days. Both sizes of Se-ENNs were taken up in the fish, however only the 120 nm Se-ENNs were detected in the brains of fish. Zebrafish fed with Se-ENNs supplemented diets (60 and 120 nm) showed normal swimming behavior compared to the control. No significant alteration was determined in the AChE activity of the fish fed with the Se-ENNs supplemented diet. In contrast, feeding the zebrafish with a diet containing 240 mg kg(-1)Se led to lethal effects. These observations clearly depict the potential benefits of using Se-ENNs as nutrients in fish feed.

Place, publisher, year, edition, pages
Royal Society of Chemistry , 2020. Vol. 7, no 8, p. 2325-2336
National Category
Environmental Sciences
Identifiers
URN: urn:nbn:se:oru:diva-85280DOI: 10.1039/d0en00240bISI: 000558930600008Scopus ID: 2-s2.0-85089890753OAI: oai:DiVA.org:oru-85280DiVA, id: diva2:1463318
Note

Funding Agencies:

European Union (EU) 652831

ERDF "Multidisciplinary research to increase application potential of nanomaterials in agricultural practice" CZ.02.1.01/0.0/0.0/16_025/0007314

Grant Agency of the Czech Republic 17-15451S

Available from: 2020-09-01 Created: 2020-09-01 Last updated: 2023-12-08Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Authority records

Chupani, Latifeh

Search in DiVA

By author/editor
Chupani, LatifehRichtera, Lukas
By organisation
School of Science and Technology
Environmental Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 53 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf