Bone Mineral Density, Parathyroid Hormone, and Vitamin D After Gastric Bypass Surgery: a 10-Year Longitudinal Follow-Up
2020 (English)In: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 30, no 12, p. 4995-5000Article in journal (Refereed) Published
Abstract [en]
BACKGROUND: The aim of the present study was to study longitudinal changes in bone mineral density (BMD), vitamin D, and parathyroid hormone (PTH) levels in females over a 10-year period after laparoscopic Roux-en-Y gastric bypass (LRYGB).
METHODS: at baseline, were included. BMD, BMI, S-calcium, S-25(OH)-vitamin D, and fP-PTH were measured preoperatively and 2, 5, and 10 years postoperatively.
RESULTS: Ten years after surgery, BMD of the spine and femoral neck decreased by 20% and 25%, respectively. Changes in serum levels of vitamin D, PTH, and calcium over the same period were small.
CONCLUSION: After LRYGB with subsequent massive weight loss, a large decrease in BMD of the spine and femoral neck was seen over a 10-year postoperative period. The fall in BMD largely occurred over the first 5 years after surgery.
Place, publisher, year, edition, pages
Springer, 2020. Vol. 30, no 12, p. 4995-5000
Keywords [en]
BMI, Bone health, Bone mineral density, Gastric bypass, Obesity, Parathyroid hormone, Vitamin D
National Category
Orthopaedics
Identifiers
URN: urn:nbn:se:oru:diva-85323DOI: 10.1007/s11695-020-04912-7ISI: 000563598800001PubMedID: 32860128Scopus ID: 2-s2.0-85089973154OAI: oai:DiVA.org:oru-85323DiVA, id: diva2:1465036
Note
Funding Agencies:
Örebro University
Lisa & Johan Grönbergs stiftelse, Stockholm
2020-09-082020-09-082023-12-08Bibliographically approved