To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Comparison of reliability of magnetic resonance imaging using cartilage and T1-weighted sequences in the assessment of the closure of the growth plates at the knee
Department of Pediatric Radiology, Karolinska University Hospital, Stockholm, Sweden; Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden.ORCID iD: 0000-0002-8730-5901
Department of Health, Blekinge Institute of Technology, Karlskrona, Sweden.
Örebro University, School of Medical Sciences. Karolinska Inst, Dept Womens & Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, SwedenHlth, Stockholm, Sweden.;Orebro Univ, Sch Med Sci, Orebro, Sweden..ORCID iD: 0000-0002-9986-8138
Department of Health, Blekinge Institute of Technology, Karlskrona, Sweden.ORCID iD: 0000-0001-9870-8477
Show others and affiliations
2020 (English)In: Acta Radiologica Open, E-ISSN 2058-4601, Vol. 9, no 9, article id 2058460120962732Article in journal (Refereed) Published
Abstract [en]

Background: Growth development is traditionally evaluated with plain radiographs of the hand and wrist to visualize bone structures using ionizing radiation. Meanwhile, MRI visualizes bone and cartilaginous tissue without radiation exposure.

Purpose: To determine the state of growth plate closure of the knee in healthy adolescents and young adults and compare the reliability of staging using cartilage sequences and T1-weighted (T1W) sequence between pediatric and general radiologists.

Material and Methods: A prospective, cross-sectional study of MRI of the knee with both cartilage and T1W sequences was performed in 395 male and female healthy subjects aged between 14.0 and 21.5 years old. The growth plate of the femur and the tibia were graded using a modified staging scale by two pediatric and two general radiologists. Femur and tibia were graded separately with both sequences.

Results: The intraclass correlation was overall excellent. The inter- and intra-observer agreement for pediatric radiologists on T1W was 82% (kappa = 0.73) and 77% (kappa = 0.65) for the femur and 90% (kappa = 0.82) and 87% (kappa = 0.75) for the tibia. The inter-observer agreement for general radiologists on T1W was 69% (kappa = 0.56) for the femur and 56% (kappa = 0.34) for the tibia. Cohen's kappa coefficient showed a higher inter- and intra-observer agreement for cartilage sequences than for T1W: 93% (kappa = 0.86) and 89% (kappa = 0.79) for the femur and 95% (kappa = 0.90) and 91% (kappa = 0.81) for the tibia.

Conclusion: Cartilage sequences are more reliable than T1W sequence in the assessment of the growth plate in adolescents and young adults. Pediatric radiology experience is preferable.

Place, publisher, year, edition, pages
Sage Publications, 2020. Vol. 9, no 9, article id 2058460120962732
Keywords [en]
Growth plate, cartilage, MRI of the knee, growth failure, growth development
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:oru:diva-86645DOI: 10.1177/2058460120962732ISI: 000574701900001PubMedID: 33088592OAI: oai:DiVA.org:oru-86645DiVA, id: diva2:1477813
Available from: 2020-10-20 Created: 2020-10-20 Last updated: 2022-04-20Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records

Nilsson, Ola

Search in DiVA

By author/editor
Kvist, Ola F. T.Nilsson, OlaAnderberg, PeterFlodmark, Carl-Erik
By organisation
School of Medical Sciences
In the same journal
Acta Radiologica Open
Radiology, Nuclear Medicine and Medical Imaging

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 125 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf