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Home phototherapy for hyperbilirubinemia in term neonates: an unblinded multicentre randomized controlled trial
Örebro University, School of Medical Sciences.ORCID iD: 0000-0003-3762-7627
Örebro University, School of Health Sciences.ORCID iD: 0000-0002-5996-2584
Department of Pediatrics, Karlstad Hospital, Karlstad, Sweden.
Örebro University, School of Medical Sciences. Örebro University Hospital.ORCID iD: 0000-0003-0531-6189
2021 (English)In: European Journal of Pediatrics, ISSN 0340-6199, E-ISSN 1432-1076, Vol. 180, no 5, p. 1603-1610Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to assess whether home phototherapy was feasible and safe in a cohort of otherwise healthy term-born neonates who fulfilled the criteria for in-hospital phototherapy. This was a randomized controlled trial in which term newborns with a total serum bilirubin of 18–24 mg/dL (300–400 μmol) were randomized to either home phototherapy or conventional in-hospital phototherapy. The primary outcome measurements were safety and efficacy, length of stay and the number of failed treatments. The secondary outcomes were the number of blood samples and weight gain during treatment. One hundred forty-seven patients were recruited, 69 patients randomized to conventional phototherapy and 78 to home phototherapy. The results showed that no patients needed blood exchange and only 4% of the patients allocated to home phototherapy were admitted to the hospital. The duration of phototherapy, length of stay, amount of blood tests and weight change showed no statically significant differences.

Conclusion: Home phototherapy could be a safe alternative to inpatient phototherapy for otherwise healthy newborns with hyperbilirubinemia if daily checkups and 24/7 telephone support can be provided. The parents should be informed to contact the hospital immediately if they fail to perform the treatment at home.

Place, publisher, year, edition, pages
Springer, 2021. Vol. 180, no 5, p. 1603-1610
Keywords [en]
Neonatal jaundice, Home phototherapy, Total serum bilirubin
National Category
Pediatrics Nursing
Research subject
Pediatrics; Caring Sciences w. Medical Focus
Identifiers
URN: urn:nbn:se:oru:diva-88723DOI: 10.1007/s00431-021-03932-4ISI: 000608929900001PubMedID: 33469713Scopus ID: 2-s2.0-85100215281OAI: oai:DiVA.org:oru-88723DiVA, id: diva2:1519998
Note

Funding Agency:

Örebro University - Uppsala and Örebro regional county council  

Available from: 2021-01-19 Created: 2021-01-19 Last updated: 2021-05-26Bibliographically approved

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Pettersson, MiriamEriksson, MatsOhlin, Andreas

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