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The World Federation of ADHD International Consensus Statement: 208 Evidence-based Conclusions about the Disorder
Departments of Psychiatry and Neuroscience and Physiology, Psychiatry Research Division, SUNY Upstate Medical University, Syracuse, NY, USA; World Federation of ADHD; American Professional Society of ADHD and Related Disorders (APSARD), USA.
Örebro University, School of Medical Sciences. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.ORCID iD: 0000-0002-6851-3297
Asian Federation of ADHD; Peking University Sixth Hospital/Institute of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China; NHC Key Laboratory of Mental Health (Peking University), Beijing, China.
Number of Authors: 792021 (English)In: Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, E-ISSN 1873-7528, Vol. 128, p. 789-818Article, review/survey (Refereed) Published
Abstract [en]

BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base.

METHODS: We reviewed studies with more than 2,000 participants or meta-analyses from five or more studies or 2,000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder.

RESULTS: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 79 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 362 people who have read this document and agree with its contents.

CONCLUSIONS: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Place, publisher, year, edition, pages
Pergamon Press, 2021. Vol. 128, p. 789-818
Keywords [en]
ADHD, brain, course, diagnosis, genetics, outcome, treatment
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-89420DOI: 10.1016/j.neubiorev.2021.01.022ISI: 000680162000005PubMedID: 33549739Scopus ID: 2-s2.0-85103736896OAI: oai:DiVA.org:oru-89420DiVA, id: diva2:1526505
Funder
Wellcome trustEuropean Commission
Note

Funding agencies:

United States Department of Health & Human Services

National Institutes of Health (NIH) - USA

NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development  (NICHD) R03 HD087091  

NIH National Institute of Environmental Health Sciences (NIEHS)R01 ES026993  United States Department of Health & Human Services

NIH National Institute of Mental Health (NIMH)U01 MH109536  

R01 MH113855  R61 MH110043  R01 MH091068  R01 MH101519 

Available from: 2021-02-08 Created: 2021-02-08 Last updated: 2021-08-23Bibliographically approved

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Larsson, Henrik

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