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ADHD and accidents over the life span: a systematic review
Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Frankfurt, Goethe University, Frankfurt/Main, Germany.
Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Frankfurt, Goethe University, Frankfurt/Main, Germany.
Örebro University, School of Medical Sciences. Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.ORCID iD: 0000-0002-6851-3297
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2021 (English)In: Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, E-ISSN 1873-7528, Vol. 125, p. 582-591Article, review/survey (Refereed) Published
Abstract [en]

Studies have demonstrated an increased risk of accidents and injuries in children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD). However, little is known about how accident risk may alter over the lifespan. Additionally, it would be important to know if the most common types of accidents and injuries differ in ADHD patients over different age groups. Furthermore, there is increasing evidence of an ameliorating effect of ADHD medication on accident risk. Lastly, the underlying risk factors and causal mechanisms behind increased accident risk remain unclear. We therefore conducted a systematic review focusing on the above described research questions. Our results suggested that accident/injury type and overall risk changes in ADHD patients over the lifespan. ADHD medication appeared to be similarly effective at reducing accident risk in all age groups. However, studies with direct comparisons of accident/injuries and effects of medication at different age groups or in old age are still missing. Finally, comorbidities associated with ADHD such as substance abuse appear to further increase the accident/injury risk.

Place, publisher, year, edition, pages
Pergamon Press, 2021. Vol. 125, p. 582-591
Keywords [en]
ADHD, accidents, amphetamine, atomoxetine, injuries, methylphenidate, stimulant, trajectories
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-89570DOI: 10.1016/j.neubiorev.2021.02.002ISI: 000646748800009PubMedID: 33582234Scopus ID: 2-s2.0-85102560839OAI: oai:DiVA.org:oru-89570DiVA, id: diva2:1528257
Note

Funding Agency:

European Commission 667302 728018

Available from: 2021-02-15 Created: 2021-02-15 Last updated: 2021-06-03Bibliographically approved

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Larsson, Henrik

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