To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The mortality burden in patients with hip fractures and dementia
Örebro University, School of Medical Sciences. Department of Orthopedic Surgery, Örebro University Hospital, Örebro, Sweden.
Örebro University, School of Medical Sciences. Department of Orthopedic Surgery, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0003-3436-1026
Örebro University, School of Medical Sciences. Department of Orthopedic Surgery, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0003-3583-3443
Örebro University, School of Medical Sciences. Division of Trauma & Emergency Surgery, Department of Surgery, Karolinska University Hospital, Stockholm, Sweden.
Show others and affiliations
2022 (English)In: European Journal of Trauma and Emergency Surgery, ISSN 1863-9933, E-ISSN 1863-9941, Vol. 48, no 4, p. 2919-2952Article in journal (Refereed) Published
Abstract [en]

PURPOSE: Dementia is strongly associated with postoperative death in patients subjected to hip fracture surgery. Nevertheless, there is a distinct lack of research investigating the cause of postoperative mortality in patients with dementia. This study aims to investigate the distribution and the risk of cause-specific postoperative mortality in patients with dementia compared to the general hip fracture population.

METHODS: All adults who underwent emergency hip fracture surgery in Sweden between 1/1/2008 and 31/12/2017 were considered for inclusion. Pathological, conservatively managed fractures, and reoperations were excluded. The database was retrieved by cross-referencing the Swedish National Quality Registry for Hip Fracture patients with the Swedish National Board of Health and Welfare quality registers. A Poisson regression model was used to determine the association between dementia and all-cause as well as cause-specific 30-day postoperative mortality.

RESULTS: 134,915 cases met the inclusion criteria, of which 20% had dementia at the time of surgery. The adjusted risk of all-cause 30-day postoperative mortality was 67% higher in patients with dementia after hip fracture surgery compared to patients without dementia [adj. IRR (95% CI): 1.67 (1.60-1.75), p < 0.001]. The risk of cause-specific mortality was also higher in patients with dementia, with up to a sevenfold increase in the risk cerebrovascular mortality [adj. IRR (95% CI): 7.43 (4.99-11.07), p < 0.001].

CONCLUSIONS: Hip fracture patients with dementia have a higher risk of death in the first 30 days postoperatively, with a substantially higher risk of mortality due to cardiovascular, respiratory, and cerebrovascular events, compared to patients without dementia.

Place, publisher, year, edition, pages
Urban und Vogel Medien und Medizin Verlagsgesellsc , 2022. Vol. 48, no 4, p. 2919-2952
Keywords [en]
Cause-specific mortality, Dementia, Hip fracture, Postoperative mortality
National Category
Orthopaedics
Identifiers
URN: urn:nbn:se:oru:diva-90032DOI: 10.1007/s00068-021-01612-4ISI: 000622707200001PubMedID: 33638650Scopus ID: 2-s2.0-85101857216OAI: oai:DiVA.org:oru-90032DiVA, id: diva2:1532021
Note

Funding Agency:

Örebro University  

Available from: 2021-03-01 Created: 2021-03-01 Last updated: 2024-03-06Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Ioannidis, IoannisMohammad Ismail, AhmadForssten, Maximilian PeterAhl, RebeckaCao, YangBorg, TomasMohseni, Shahin

Search in DiVA

By author/editor
Ioannidis, IoannisMohammad Ismail, AhmadForssten, Maximilian PeterAhl, RebeckaCao, YangBorg, TomasMohseni, Shahin
By organisation
School of Medical SciencesÖrebro University Hospital
In the same journal
European Journal of Trauma and Emergency Surgery
Orthopaedics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 270 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf