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Adaptation of the Charlson Comorbidity Index for Register-Based Research in Sweden
Örebro University, School of Medical Sciences. Örebro University Hospital. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA.ORCID iD: 0000-0003-1024-5602
University Health Care Research Center, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Rheumatology, Theme Inflammation and Infection, Karolinska University Hospital, Stockholm, Sweden.
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
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2021 (English)In: Clinical Epidemiology, E-ISSN 1179-1349, Vol. 13, p. 21-41Article in journal (Refereed) Published
Abstract [en]

Purpose: Comorbidity indices are often used to measure comorbidities in register-based research. We aimed to adapt the Charlson comorbidity index (CCI) to a Swedish setting.

Methods: Four versions of the CCI were compared and evaluated by disease-specific experts.

Results: We created a cohesive coding system for CCI to 1) harmonize the content between different international classification of disease codes (ICD-7,8,9,10), 2) delete incorrect codes, 3) enhance the distinction between mild, moderate or severe disease (and between diabetes with and without end-organ damage), 4) minimize duplication of codes, and 5) briefly explain the meaning of individual codes in writing.

Conclusion: This work may provide an integrated and efficient coding algorithm for CCI to be used in medical register-based research in Sweden.

Place, publisher, year, edition, pages
Dove Medical Press Ltd. , 2021. Vol. 13, p. 21-41
Keywords [en]
Charlson comorbidity score, comorbidity, disease, epidemiology, public health, Sweden
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:oru:diva-90442DOI: 10.2147/CLEP.S282475ISI: 000614055700001PubMedID: 33469380Scopus ID: 2-s2.0-85099720348OAI: oai:DiVA.org:oru-90442DiVA, id: diva2:1537332
Available from: 2021-03-15 Created: 2021-03-15 Last updated: 2024-07-04Bibliographically approved

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Ludvigsson, Jonas F.

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