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Patients over 65 years with Acute Complicated Calculous Biliary Disease are Treated Differently: Results and Insights from the ESTES Snapshot Audit
Örebro University, School of Medical Sciences. Division of Traumatology, Emergency Surgery & Surgical Critical Care, Penn Presbyterian Medical Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Surgery, Tallaght University Hospital, Dublin, Ireland.ORCID iD: 0000-0002-1918-9443
Department of Surgery, Tallaght University Hospital, Dublin, Ireland.
Örebro University, School of Medical Sciences. Örebro University Hospital. (Clinical Epidemiology and Biostatistics)ORCID iD: 0000-0002-3552-9153
Örebro University, School of Medical Sciences. Örebro University Hospital. Division of Trauma and Emergency Surgery, Department of Surgery, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0001-7097-487X
2021 (English)In: World Journal of Surgery, ISSN 0364-2313, E-ISSN 1432-2323, Vol. 45, no 7, p. 2046-2055Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Accrued comorbidities are perceived to increase operative risk. Surgeons may offer operative treatments less often to their older patients with acute complicated calculous biliary disease (ACCBD). We set out to capture ACCBD incidence in older patients across Europe and the currently used treatment algorithms.

METHODS: The European Society of Trauma and Emergency Surgery (ESTES) undertook a snapshot audit of patients undergoing emergency hospital admission for ACCBD between October 1 and 31 2018, comparing patients under and ≥ 65 years. Mortality, postoperative complications, time to operative intervention, post-acute disposition, and length of hospital stay (LOS) were compared between groups. Within the ≥ 65 cohort, comorbidity burden, mortality, LOS, and disposition outcomes were further compared between patients undergoing operative and non-operative management.

RESULTS: The median age of the 338 admitted patients was 67 years; 185 patients (54.7%) of these were the age of 65 or over. Significantly fewer patients ≥ 65 underwent surgical treatment (37.8% vs. 64.7%, p < 0.001). Surgical complications were more frequent in the ≥ 65 cohort than younger patients, and the mean postoperative LOS was significantly longer. Postoperative mortality was seen in 2.2% of patients ≥ 65 (vs. 0.7%, p = 0.253). However, operated elderly patients did not differ from non-operated in terms of comorbidity burden, mortality, LOS, or post-discharge rehabilitation need.

CONCLUSIONS: Few elderly patients receive surgical treatment for ACCBD. Expectedly, postoperative morbidity, LOS, and the requirement for post-discharge rehabilitation are higher in the elderly than younger patients but do not differ from elderly patients managed non-operatively. With multidisciplinary perioperative optimization, elderly patients may be safely offered optimal treatment.

TRIAL REGISTRATION: ClinicalTrials.gov (Trial # NCT03610308).

Place, publisher, year, edition, pages
Springer, 2021. Vol. 45, no 7, p. 2046-2055
National Category
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-90985DOI: 10.1007/s00268-021-06052-0ISI: 000636398600002PubMedID: 33813631Scopus ID: 2-s2.0-85103660236OAI: oai:DiVA.org:oru-90985DiVA, id: diva2:1544071
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Funding Agency:

Örebro University  

Available from: 2021-04-14 Created: 2021-04-14 Last updated: 2024-03-06Bibliographically approved

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Bass, G. A.Cao, YangMohseni, Shahin

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