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Adverse Pregnancy Outcomes in Women Diagnosed with ADHD: A Population-Based Register Study
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-9375-6303
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-4811-2330
Örebro University, School of Law, Psychology and Social Work.ORCID iD: 0000-0002-1704-9543
Örebro University, School of Law, Psychology and Social Work. Department of Psychology, University of Southern California, United States.ORCID iD: 0000-0001-8768-6954
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(English)Manuscript (preprint) (Other academic)
National Category
General Practice
Identifiers
URN: urn:nbn:se:oru:diva-91754OAI: oai:DiVA.org:oru-91754DiVA, id: diva2:1553683
Available from: 2021-05-10 Created: 2021-05-10 Last updated: 2021-05-17Bibliographically approved
In thesis
1. How is ADHD associated with comorbidities and health related outcomes?: The role of familial factors and ADHD during pregnancy
Open this publication in new window or tab >>How is ADHD associated with comorbidities and health related outcomes?: The role of familial factors and ADHD during pregnancy
2021 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by impaired attention and hyperactivity/impulsivity. ADHD is associated with several comorbidities and health-related outcomes. However, it is uncertain whether ADHD is more strongly associated with certain disorder domains, and whether ADHD-related comorbidities and health-related outcomes is important to consider during pregnancy. 

Aims: To expand the knowledge regarding the genetic overlap between ADHD and other psychiatric disorder symptoms, and to increase the awareness and understanding related to ADHD in women, with a focus on adverse health behaviors, mental health problems, and pregnancy outcomes. 

Methods: The present thesis includes one systematic review and metaanalysis (Study I), and three studies based on population-based register data from Sweden (Study II, III, and IV), and Norway (Study II).

Results: Individuals with ADHD have an increased liability to meet criteria for externalizing, internalizing and neurodevelopmental disordersymptoms, and these co-occurrences are partly due to shared genetic risks. Further, ADHD is an important risk factor to consider before, during and after pregnancy, as ADHD increases the risk of smoking during pregnancy, mental health problems postpartum, and adverse pregnancy outcomes.

Conclusions: The genetic overlaps between ADHD and other psychiatric disorder symptoms were similar across disorder dimensions. Further, results demonstrated that ADHD is an important risk factor to consider in women surrounding pregnancy. These findings point towards the importance of recognizing that women diagnosed with ADHD need to be prioritized and allowed more attention and support by the healthcare system, specifically during their fertile years. 

Place, publisher, year, edition, pages
Örebro: Örebro University, 2021. p. 49
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 238
Keywords
ADHD, Comorbidities, Health-Related, Pregnancy, Smoking, Psychiatric, Postpartum, Outcomes
National Category
General Practice
Identifiers
urn:nbn:se:oru:diva-90510 (URN)978-91-7529-386-8 (ISBN)
Public defence
2021-06-04, Örebro universitet, Campus USÖ, hörsal C1, Södra Grev Rosengatan 32, Örebro, 09:00 (Swedish)
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Supervisors
Available from: 2021-03-17 Created: 2021-03-17 Last updated: 2021-06-03Bibliographically approved

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Andersson, AnneliGarcia-Argibay, MiguelOskarsson, SofiTuvblad, CatherineLarsson, Henrik

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