oru.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Identification and pattern of perfluorooctane sulfonate (PFOS) isomers in human serum and plasma
Örebro University, Department of Natural Sciences. (MTM)
Örebro University, Department of Natural Sciences. (MTM)ORCID iD: 0000-0001-6217-8857
Örebro University, Department of Natural Sciences. (MTM)ORCID iD: 0000-0002-4959-2807
Show others and affiliations
2007 (English)In: Environment International, ISSN 0160-4120, E-ISSN 1873-6750, Vol. 33, no 6, p. 782-788Article in journal (Refereed) Published
Abstract [en]

Human serum and plasma from Sweden (n=17), the United Kingdom (the UK) (n=13) and Australia (n=40) were analyzed by high performance liquid chromatography coupled to mass spectrometry. The objective was to identify different perfluorooctane sulfonate (PFOS) isomers. Similar isomer patterns typical for the electrochemical fluorination (ECF) process were found for all samples. The linear PFOS (L-PFOS) was the major isomer found (58-70%) followed by the monosubstituted PFOS isomers 1/6-CF(3)-PFOS (18-22%) and 3/4/5-CF(3)-PFOS (13-18%). Disubstituted isomers were also detected. The percentage of L-PFOS found in the serum and plasma samples was lower compared to a standard PFOS product (76-79%). The pattern of PFOS isomers in human serum and plasma may be suggestive concerning potential isomeric discrimination since PFOS is only produced by ECF. Possibilities for such isomer discrimination are discussed. Significant higher content of L-PFOS (68%) in Swedish samples compared to Australia and the UK (59%) was also found, which may suggest differences in exposure sources for humans.

Place, publisher, year, edition, pages
2007. Vol. 33, no 6, p. 782-788
National Category
Natural Sciences Medical and Health Sciences Chemical Sciences
Research subject
Chemistry
Identifiers
URN: urn:nbn:se:oru:diva-5305DOI: 10.1016/j.envint.2007.02.015PubMedID: 17442394OAI: oai:DiVA.org:oru-5305DiVA, id: diva2:158669
Available from: 2009-02-03 Created: 2009-02-03 Last updated: 2017-12-14Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Kärrman, Annavan Bavel, BertLindström, Gunilla

Search in DiVA

By author/editor
Kärrman, Annavan Bavel, BertLindström, Gunilla
By organisation
Department of Natural Sciences
In the same journal
Environment International
Natural SciencesMedical and Health SciencesChemical Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 475 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf