To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Daytime urotherapy in nocturnal enuresis: a randomised, controlled trial
Center for Clinical Research Dalarna, Falun, Sweden; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Örebro University, School of Medical Sciences. Center for Clinical Research Dalarna, Uppsala University, Falun, Sweden.
Show others and affiliations
2022 (English)In: Archives of Disease in Childhood, ISSN 0003-9888, E-ISSN 1468-2044, Vol. 107, no 6, p. 570-574Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: According to international guidelines, children with enuresis are recommended urotherapy, or basic bladder advice, before treatment with evidence-based alternatives such as the enuresis alarm is given. The efficacy of this strategy has, however, not been supported by controlled studies. We wanted to test if basic bladder advice is useful in enuresis.

DESIGN: Randomised, controlled trial.

SETTING: Paediatric outpatient ward, regional hospital.

PATIENTS: Treatment-naïve enuretic children aged ≥6 years, with no daytime incontinence.

INTERVENTIONS: Three groups, each during 8 weeks: (A) basic bladder advice-that is, voiding and drinking according to a strict schedule and instructions regarding toilet posture, (B) enuresis alarm therapy and (C) no treatment (control group).

MAIN OUTCOME MEASURES: Reduction in enuresis frequency during week 7-8 compared with baseline.

RESULTS: The median number of wet nights out of 14 before and at the end of treatment were in group A (n=20) 12.5 and 11.5 (p=0.44), in group B (n=22) 11.0 and 3.5 (p<0.001) and in group C (n=18) 12.5 and 12.0 (p=0.55). The difference in reduction of enuresis frequency between the groups was highly significant (p=0.002), but no difference was found between basic bladder advice and controls.

CONCLUSIONS: Urotherapy, or basic bladder advice, is ineffective as a first-line treatment of nocturnal enuresis. Enuretic children who are old enough to be bothered by their condition should be offered treatment with the alarm or desmopressin.

TRIAL REGISTRATION NUMBER: NCT03812094.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2022. Vol. 107, no 6, p. 570-574
Keywords [en]
Enuresis, nephrology, paediatrics
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:oru:diva-96813DOI: 10.1136/archdischild-2021-323488ISI: 000747344800001PubMedID: 35074830Scopus ID: 2-s2.0-85130765535OAI: oai:DiVA.org:oru-96813DiVA, id: diva2:1633126
Funder
Gillbergska stiftelsen
Note

Funding agency:

Swedish Enuresis Academy

Available from: 2022-01-28 Created: 2022-01-28 Last updated: 2022-08-29Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Skogman, Barbro Hedin

Search in DiVA

By author/editor
Skogman, Barbro Hedin
By organisation
School of Medical Sciences
In the same journal
Archives of Disease in Childhood
Pediatrics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 71 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf