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Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)
Department of Pharmacy, Temple University, Philadelphia, USA.
Department of Pharmacy, Temple University, Philadelphia, USA.
Cardiology, Native Cardio Inc., Naples, USA.
Department of Pharmacy, Temple University, Philadelphia, USA.
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2022 (English)In: Cureus, E-ISSN 2168-8184, Vol. 14, no 3, article id e22778Article, review/survey (Refereed) Published
Abstract [en]

In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF therapies, digoxin was widely used for symptomatic relief on these patients. Further randomized trials are required to reach a definite conclusion about its efficacy and safety in patients experiencing HF with a reduced EF (HFrEF).

Place, publisher, year, edition, pages
Cureus Inc. , 2022. Vol. 14, no 3, article id e22778
Keywords [en]
cv, cardiovascular, readmission, rehospitalization, mortality, reduced ejection fraction, digitalis, heart failure, digoxin, hfref
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:oru:diva-98504DOI: 10.7759/cureus.22778ISI: 000770046900002PubMedID: 35371861OAI: oai:DiVA.org:oru-98504DiVA, id: diva2:1650377
Available from: 2022-04-07 Created: 2022-04-07 Last updated: 2023-01-25Bibliographically approved

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Magnusson, Peter

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