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Nuts and Metabolic Syndrome: Reducing the Burden of Metabolic Syndrome in Menopause
Service of Obstetrics and Gynecology, Hospital Clínico-INCLIVA, 46010 Valencia, Spain.
Service of Obstetrics and Gynecology, Hospital Clínico-INCLIVA, 46010 Valencia, Spain.
Service of Obstetrics and Gynecology, Hospital Clínico-INCLIVA, 46010 Valencia, Spain.
Service of Obstetrics and Gynecology, Hospital Clínico-INCLIVA, 46010 Valencia, Spain.
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2022 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 14, no 8, article id 1677Article, review/survey (Refereed) Published
Abstract [en]

Menopause imposes a dramatic fall in estrogens, which is followed by an increase in the proportion of fat. The rising androgen/estrogen ratio along the menopause transition favors the accumulation of central fat, which contributes to insulin resistance and a series of concatenated effects, leading to a higher incidence of metabolic syndrome. The modulatory effect of diet on the metabolic syndrome phenotype has been shown for the Mediterranean diet, and nuts are key determinants of these health benefits. This review of the impact of nuts on the risk factors of the metabolic syndrome cluster examined studies-prioritizing meta-analyses and systemic reviews-to summarize the potential benefits of nut ingestion on the risk of metabolic syndrome associated with menopause. Nuts have a general composition profile that includes macronutrients, with a high proportion of unsaturated fat, bioactive compounds, and fiber. The mechanisms set in motion by nuts have shown different levels of efficacy against the disturbances associated with metabolic syndrome, but a beneficial impact on lipids and carbohydrate metabolism, and a potential, but minimal reduction in blood pressure and fat accumulation have been found.

Place, publisher, year, edition, pages
MDPI, 2022. Vol. 14, no 8, article id 1677
Keywords [en]
menopause, metabolic syndrome, nuts, women
National Category
Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:oru:diva-98785DOI: 10.3390/nu14081677ISI: 000787957700001PubMedID: 35458240Scopus ID: 2-s2.0-85128510306OAI: oai:DiVA.org:oru-98785DiVA, id: diva2:1655262
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EU, Horizon 2020, 696300Available from: 2022-05-02 Created: 2022-05-02 Last updated: 2023-08-28Bibliographically approved

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Kadi, FawziNilsson, Andreas

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