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Moderators of long-term treatment outcome when comparing two group interventions for adolescents with ADHD: who benefits more from DBT-based skills training?
Department of Medical Sciences, Child and Adolescent Psychiatry Unit, Uppsala University, Uppsala, Sweden; Center of Neurodevelopmental Disorders (KIND), Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Sciences, Child and Adolescent Psychiatry Unit, Uppsala University, Uppsala, Sweden; Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Örebro University, School of Medical Sciences. Public Health Sciences, Karlstad University, Karlstad, Sweden.ORCID iD: 0000-0003-0837-1079
Department of Medical Sciences, Child and Adolescent Psychiatry Unit, Uppsala University, Uppsala, Sweden.
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2022 (English)In: BMC Psychiatry, E-ISSN 1471-244X, Vol. 22, no 1, article id 767Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Psychosocial interventions for adolescents with attention-deficit/hyperactivity disorder (ADHD), targeting emotional dysregulation and impulsive behaviors, have been requested, but the heterogeneity within this group makes it unlikely that there is one treatment that fits all. The aim of this study was to identify which adolescents with ADHD might have an effect from a structured skills training group (SSTG) based on dialectical behavioral therapy, by exploring pre-treatment characteristics as potential moderators of long-term treatment outcome.

METHODS: This study was based on follow-up data from a randomized controlled trial comparing the SSTG (n = 71) to a psychoeducational control intervention (n = 57) for adolescents with ADHD (15-18 years old). Clinical characteristics (sex, age, medication status, ADHD presentation, severity of ADHD symptom, psychiatric comorbidity, impairment of emotional dysregulation and functional impairment) were explored as potential moderators of pre-treatment to follow-up change in ADHD symptoms and functional impairment. Moderation analyses were performed using the PROCESS macro for SPSS.

RESULTS: Three moderators (severity of hyperactivity/impulsivity, conduct problems and impairment of emotional dysregulation) were identified in regard to the outcome self-rated change in ADHD symptoms. Participants with elevated pre-scores on these variables had a better effect of the SSTG than of the psychoeducational control intervention. No moderators were found in regard to the parental-rated outcomes.

CONCLUSIONS: The SSTG seems to be beneficial for adolescents with ADHD who perceive pronounced symptoms of hyperactivity/impulsivity, conduct problems and emotional dysregulation. Our findings need to be confirmed in future trials evaluating dialectical behavioral therapy-based skills training for adolescents with ADHD, where these moderators could be used as criteria for inclusion or stratification.

TRIAL REGISTRATION: https://doi.org/10.1186/ISRCTN17366720 , retrospectively registered.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2022. Vol. 22, no 1, article id 767
Keywords [en]
ADHD, Adolescents, Cognitive behavioral therapy, Dialectical behavioral therapy, Moderation, Psychoeducation
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:oru:diva-102662DOI: 10.1186/s12888-022-04435-8ISI: 000895434100001PubMedID: 36474201Scopus ID: 2-s2.0-85143437174OAI: oai:DiVA.org:oru-102662DiVA, id: diva2:1718340
Funder
Uppsala University
Note

Funding agencies:

Sven Jerring foundation

Foundation Sunnerdahl's Disability Fund

Queen Silvia's Jubilee Fund

Foundation in memory of professor Bror Gadelius

Uppsala University Hospital Research Fund (ALF), Uppsala County Council's Funds for Clinical Research, Uppsala-Örebro Regional Research Council

Available from: 2022-12-12 Created: 2022-12-12 Last updated: 2024-04-08Bibliographically approved

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Unenge Hallerbäck, Maria

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