To Örebro University

oru.seÖrebro University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Societal economic burden and determinants of costs for atopic dermatitis
Quantify Research, Stockholm, Sweden.ORCID iD: 0000-0001-5102-3358
Pfizer AB, Sollentuna, Sweden.ORCID iD: 0000-0002-5327-3198
Quantify Research, Stockholm, Sweden.ORCID iD: 0000-0002-8182-5682
Quantify Research, Stockholm, Sweden; Dermatology and Venerology, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID iD: 0000-0001-7241-8471
Show others and affiliations
2022 (English)In: JEADV Clinical Practice, E-ISSN 2768-6566, Vol. 1, no 4, p. 326-343Article in journal (Refereed) Published
Abstract [en]

Background: Atopic dermatitis (AD) is a common inflammatory skin disease while the economic burden of AD by severity is not adequately understood.

Objective: To estimate the societal economic burden and to identify cost determinants of AD.

Methods: In this population‐based, controlled cohort study in Sweden, patients with AD were identified through diagnosis codes in primary or secondary care or by dispensed medications using administrative healthcare registers. A reference cohort without AD was randomly selected from the general population. Healthcare costs (primary/secondary care visits and dispensed medication) and indirect costs (care for sick children and long‐termsick leave for adults) were calculated annually. AD patients were stratified by age (paediatric [age < 12], adolescent [12≤age < 18] or adult [age≥18]), and severity (mild‐to‐moderate [M2M] or severe AD) and matched to the reference cohort.

Results: Compared with controls, the annual mean per‐patient direct healthcare costs in the first year following diagnosis were €941 and €1259 higher in paediatric patients with M2M and severe AD, respectively. In the first year following diagnosis, the mean indirect cost for care of sick children was €69 and €78 higher per patient in M2M and severe AD, respectively. In adolescents with M2M and severe AD, direct healthcare costs were €816 and €1260 higher, respectively. In adults, healthcare costs were €1583 and €2963 higher in patients with M2M and severe AD, respectively and indirect costs were €148 and €263 higher compared with controls. Management of comorbid medical conditions was an important driver of incremental healthcare costs.Total incremental societal economic burden for AD was €351 and €96 million higher in patients with M2M and severe AD, respectively, compared to controls.

Conclusion: AD is associated with a significant societal economic burden primarily driven by the cost burden of M2M AD due to the high prevalence of this population. Regardless of severity level, management of non‐ADcomorbidities is a major driver of total costs.

Place, publisher, year, edition, pages
Wiley-Blackwell Publishing Inc., 2022. Vol. 1, no 4, p. 326-343
Keywords [en]
Atopic dermatitis, economic burden, eczema, epidemiology, healthcare costs, indirect costs, public health research
National Category
Dermatology and Venereal Diseases
Identifiers
URN: urn:nbn:se:oru:diva-102842DOI: 10.1002/jvc2.74ISI: 001332696900013Scopus ID: 2-s2.0-85181477543OAI: oai:DiVA.org:oru-102842DiVA, id: diva2:1721491
Available from: 2022-12-21 Created: 2022-12-21 Last updated: 2025-01-20Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Authority records

Metsini, Alexandra

Search in DiVA

By author/editor
Ortsäter, GustafDe Geer, AnnaRieem Dun, AlexanderGeale, KirkLindberg, IngridThyssen, Jacob Pontoppidanvon Kobyletzki, Laura B.Metsini, AlexandraHenrohn, DanNeregård, PetraCha, AmyCappelleri, Joseph C.Romero, WilliamNeary, Maureen P.
By organisation
School of Medical Sciences
Dermatology and Venereal Diseases

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 35 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf