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The Danish Rural Eye Study: prevalence of strabismus among 3785 Danish adults - a population-based cross-sectional study
Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Department of Physical Medicine & Rehabilitation, School of Medicine, University of California-Davis, Sacramento, California, USA.
Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Production, Research, and Innovation, Region Zealand, Sorø, Denmark; Department of Laboratory Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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2019 (English)In: Acta Ophthalmologica, ISSN 1755-375X, E-ISSN 1755-3768, Vol. 97, no 8, p. 784-792Article in journal (Refereed) Published
Abstract [en]

PURPOSE: To determine the prevalence of strabismus among Danish adults and to find the frequency of history of strabismus and strabismus surgery. Furthermore, to evaluate the prevalence of strabismus-associated amblyopia among participants with strabismus and to relate the results to the current national vision screening programme.

METHODS: In total, 3785 adults in the Danish Rural Eye Study underwent an interview regarding eye health, visual acuity measurement, Hirschberg test and retinal photography. Participants were categorized into groups based on their birth date in relation to the introduction of the national vision screening programme.

RESULTS: In total, the prevalence of strabismus was 1.1% (41/3785; 95% CI: 0.8-1.5); no differences were found in relation to gender or screening status. The prevalence of exotropia (XT) was 0.3% (12/3785; 95% CI: 0.2-0.6) and of esotropia (ET) 0.8% (29/3785; 95% CI: 0.5-1.1), resulting in an XT:ET ratio of 1:2.7. A history of strabismus was present in 4.6% (174/3785; 95% CI: 4.0-5.3), and a history of strabismus surgery was present in 0.8% (32/3785; 95% CI: 0.6-1.2) of the participants. Among participants with manifest strabismus, 24% had strabismus-associated amblyopia.

CONCLUSION: In this first European population-based study of strabismus prevalence in adults, the prevalence was similar to three out of five previous studies using cover test. The use of Hirschberg test may have led to an underestimation of the true prevalence. The prevalence was neither related to screening status nor gender. Our results are the first to display a predominance of ET among Caucasian Scandinavian adults.

Place, publisher, year, edition, pages
John Wiley & Sons, 2019. Vol. 97, no 8, p. 784-792
Keywords [en]
Adults, esotropia, exotropia, heterotropia, population-based, prevalence, strabismus, strabismus screening, vision screening
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:oru:diva-103795DOI: 10.1111/aos.14112ISI: 000496591800008PubMedID: 31025814Scopus ID: 2-s2.0-85064824608OAI: oai:DiVA.org:oru-103795DiVA, id: diva2:1732038
Note

Funding Agencies:

Mr. and Mrs. Johs M. Klein's Memorial Scholarship  

Naestved Hospital Foundation

Ulla and Mogens Folmer Andersen's Fund

 Edith and Henrik Henriksen's Memorial Scholarship  

Region Zealand Foundation

Available from: 2023-01-30 Created: 2023-01-30 Last updated: 2024-01-02Bibliographically approved

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Andersson Grönlund, Marita

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