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Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
Université Paris Cité, INSERM, IAME, Paris, France; APHP, Infectious Agents Department, Saint Louis Hospital, Paris, France; French National Reference Centre for bacterial STIs, Associated Laboratory for Gonococci, Paris, France.
Université Paris Cité, INSERM, IAME, Paris, France; APHP, Infectious Agents Department, Saint Louis Hospital, Paris, France; French National Reference Centre for bacterial STIs, Associated Laboratory for Gonococci, Paris, France.
Université Paris Cité, INSERM, IAME, Paris, France; APHP, Infectious Agents Department, Saint Louis Hospital, Paris, France; French National Reference Centre for bacterial STIs, Associated Laboratory for Gonococci, Paris, France.
Örebro University, School of Medical Sciences. Örebro University Hospital. WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Ӧrebro University, Ӧrebro, Sweden.
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2022 (English)In: Eurosurveillance, ISSN 1025-496X, E-ISSN 1560-7917, Vol. 27, no 50, p. 17-22Article in journal (Refereed) Published
Abstract [en]

We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC- 199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.
Place, publisher, year, edition, pages
European Centre for Disease Prevention and Control , 2022. Vol. 27, no 50, p. 17-22
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-104346DOI: 10.2807/1560-7917.ES.2022.27.50.2200899ISI: 000912382500003PubMedID: 36695466Scopus ID: 2-s2.0-85144443535OAI: oai:DiVA.org:oru-104346DiVA, id: diva2:1738223
Note

Funding agencies:

French National Public Health Agency (Saint-Maurice, France)

Örebro County Council Research Committee

Foundation for Medical Research at Örebro University Hospital, Sweden

Available from: 2023-02-21 Created: 2023-02-21 Last updated: 2023-02-21Bibliographically approved

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Jacobsson, SusanneGolparian, DanielUnemo, Magnus

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