Numerous endeavours to ensure that day-to-day healthcare is both evidence-based and person-centred have generated extensive, although partial,comprehension of what guarantees quality improvement. To address qualityissues, researchers and clinicians have developed several strategies as well asimplementation theories, models, and frameworks. However, more progress isneeded regarding how to facilitate guideline and policy implementation thatguarantees effective changes take place in a timely and safe manner. This paperconsiders experiences of engaging and supporting local facilitators inknowledge implementation. Drawing on several interventions, considering bothtraining and support, this general commentary discusses whom to engage andthe length, content, quantity, and type of support along with expectedoutcomes of facilitators’ activities. In addition, this paper suggests that patientfacilitators could help produce evidence-based and person-centred care. Weconclude that research about the roles and functions of facilitators needs toinclude more structured follow-ups and also improvement projects. This canincrease the speed of learning with respect to what works, for whom, in whatcontext, why (or why not), and with what outcomes when it comes to facilitatorsupport and tasks.