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Prevention of menstrual migraine with perimenstrual transdermal 17-β-estradiol: a randomized, placebo-controlled, double-blind crossover study
Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Division of Neurology, Department of Neuroscience and Locomotion, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
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2011 (English)In: Fertility and Sterility, ISSN 0015-0282, E-ISSN 1556-5653, Vol. 96, no 2, p. 498-500.e1Article in journal, Editorial material (Other academic) Published
Abstract [en]

The effect of treatment with percutaneous estradiol (100µg estradiol/24h) during two weeks perimenstrually on the number and severity of menstrual migraine attacks was studied in 27 women in a randomized, placebo-controlled double blind cross over trial. We were not able to demonstrate any difference between estradiol supplementation and placebo on the number or severity of migraine attacks but both  regimens showed significant effects compared to pretreatment. 

Place, publisher, year, edition, pages
Elsevier, 2011. Vol. 96, no 2, p. 498-500.e1
Keywords [en]
menstrual migraine, estradiol, RCT
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:oru:diva-107890DOI: 10.1016/j.fertnstert.2011.05.089ISI: 000293008700072PubMedID: 21704313Scopus ID: 2-s2.0-79960631558OAI: oai:DiVA.org:oru-107890DiVA, id: diva2:1792276
Available from: 2023-08-29 Created: 2023-08-29 Last updated: 2024-01-02Bibliographically approved

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