BACKGROUND: Postoperative surgical site infection is a serious problem. Coverage of sterile goods may be important to protect the goods from bacterial air contamination while awaiting surgery.
AIM: We aimed to evaluate the effectiveness of this practice in a systematic review covering five databases using search terms related to bacterial contamination in the operating room and on surgical instruments.
METHODS: We searched MEDLINE, Cochrane, CINAHL, EMBASE, and Web of Science from database inception to February 13, 2023, for randomized and non-randomized controlled studies of covering interventions conducted in the operating room setting. The outcome was bacterial air contamination measured as colony forming units, and a meta-analysis was performed in separate time periods of coverage. This systematic review and meta-analysis is reported according to the PRISMA statement, and the protocol was prospectively registered in PROSPERO (CRD42022323113). The time points ranged from 30 minutes to 24 hours.
FINDINGS: The results showed that covering sterile goods significantly prevented bacterial air contamination as compared to uncovered goods. The meta-analysis was in favour of covering sterile goods for protection from bacterial air contamination, and showed an effect size Z of 4.76 (p<0.00001, CI: -1.94 to -0.81). The heterogeneity analysis showed a heterogeneity of 83%.
CONCLUSION: No negative effects regarding bacterial contamination were found, and so we conclude that protection with a sterile cover decreases bacterial air contamination of sterile goods while waiting for surgery to start.
Academic Press, 2024. Vol. 145, p. 106-117
Infection Control, bacterial air contamination, operating room, review, sterile covers