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Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing
Division of AIDS and STIs, Department of Disease Control and Prevention, Bangrak STIs Center, Thailand Ministry of Public Health, Bangkok, Thailand.
Örebro University, School of Medical Sciences. Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, World Health Organization (WHO) Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Örebro University, Örebro, Sweden.ORCID iD: 0000-0002-0688-2521
Division of AIDS and STIs, Department of Disease Control and Prevention, Bangrak STIs Center, Thailand Ministry of Public Health, Bangkok, Thailand.
Division of AIDS and STIs, Department of Disease Control and Prevention, Bangrak STIs Center, Thailand Ministry of Public Health, Bangkok, Thailand.
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2024 (English)In: Microbiology Resource Announcements, E-ISSN 2576-098X, Vol. 13, no 3, article id e0123123Article in journal (Refereed) Published
Abstract [en]

Ceftriaxone-resistant Neisseria gonorrhoeae strains, mostly associated with Asia, threaten gonorrhea treatment. We report the reference genomes of two ceftriaxone-resistant isolates found in routine surveillance in Bangkok, Thailand. The genomes belonged to the more antimicrobial-susceptible genomic lineage B, illustrating that both ceftriaxone-resistant strains and the mosaic penA-60.001 ceftriaxone-resistance determinant are spreading.
Place, publisher, year, edition, pages
American Society for Microbiology, 2024. Vol. 13, no 3, article id e0123123
Keywords [en]
Neisseria gonorrhoeae, Thailand, ceftriaxone resistance
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-111350DOI: 10.1128/mra.01231-23ISI: 001155697800001PubMedID: 38299807Scopus ID: 2-s2.0-85188013896OAI: oai:DiVA.org:oru-111350DiVA, id: diva2:1834132
Funder
Region Örebro County
Note

The present work was funded by grants from the Bangrak STIs Center, Bangkok, Thailand; WHO Thailand; Örebro County Council Research Committee; and the Foundation for Medical Research at Örebro University Hospital, Sweden.

Available from: 2024-02-02 Created: 2024-02-02 Last updated: 2025-01-20Bibliographically approved

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Golparian, DanielUnemo, Magnus

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