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Geographical variations in the effectiveness and safety of abbreviated or standard antiplatelet therapy after PCI in patients at high bleeding risk
Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Severance Cardiovascular Hospital, Yonsei University College of Medicine, South Korea.
Clinical Trial Unit, University of Bern, Bern, Switzerland.
Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
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2024 (English)In: Canadian Journal of Cardiology, ISSN 0828-282X, E-ISSN 1916-7075, Vol. 40, no 9, p. 1671-1674Article in journal (Refereed) Published
Abstract [en]

In high-bleeding risk (HBR) patients, non-inferiority of 1-month dual antiplatelet therapy (APT) to treatment continuation for ≥2 additional months for the occurrence of net and major adverse clinical events after drug-eluting stent implantation was showed in the MASTER DAPT trial.1 A significant reduction in bleeding was also noted. However, whether these treatment effects of APT are consistent across geographical regions remains uncertain. In the present analyses, the effects of abbreviated or standard APT on the 1-year occurrence of net and major adverse clinical events and bleeding were consistent across geographical regions (Europe, East Asia, and others) [NCT03023020].

Place, publisher, year, edition, pages
Elsevier, 2024. Vol. 40, no 9, p. 1671-1674
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:oru:diva-111382DOI: 10.1016/j.cjca.2024.01.032ISI: 001313457800001PubMedID: 38309468Scopus ID: 2-s2.0-85197075919OAI: oai:DiVA.org:oru-111382DiVA, id: diva2:1834590
Note

The study was sponsored by the European Cardiovascular Research Institute, a nonprofit organization, and received grant support from Terumo. 

Available from: 2024-02-05 Created: 2024-02-05 Last updated: 2024-09-26Bibliographically approved

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Fröbert, Ole

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