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Trends in the incidence and prevalence of menopausal hormone therapy in Sweden from 2000 to 2021
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden; Department of Obstetrics and Gynecology, Kalmar County Hospital, Kalmar, Sweden.
Örebro University, School of Medical Sciences. Department of Obstetrics and Gynecology, Kalmar County Hospital, Kalmar, Sweden; Department of Obstetrics and Gynecology, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID iD: 0000-0002-0071-4383
Department of Obstetrics and Gynecology, Kalmar County Hospital, Kalmar, Sweden; Department of Obstetrics and Gynecology, Linköping University Hospital, Linköping, Sweden.
Department of Obstetrics and Gynecology, Kalmar County Hospital, Kalmar, Sweden.
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2023 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 102, no Suppl. 1, p. 70-70Article in journal, Meeting abstract (Other academic) Published
Abstract [en]

Introduction/Purpose: To describe the dynamics of incidence, prevalence and defined daily doses (DDD) of menopausal hormone therapy (MHT) in Sweden during 2000–2021 and to analyze the impact of different run-in periods on the incidence.

Methods: Swedish dispensation data on >4 million women ≥30 years in 2006–2021 was exported from the Swedish eHealth Agency as aggregated patient-level data; DDD, 1-year prevalence and incidence of MHT use were studied. The predictive values for incidence representing first-ever use of MHT were calculated for different run- in periods, with 120 months as a reference.

Results: From 2000 to 2010, the DDD and the prevalence of MHT decreased by over 80% in women aged 50–54 years. From 2018, the use increased at all ages except for the oldest, 65–69 years.

The predictive value for incident users to be true first-ever users with a run-in of 18 months was 88% in women aged 50–54 years in 2021. The incidence was stable between 2007 and 2016. From 2017 the incidence increased, being most pronounced for the ages close to menopause.

Conclusions: The use of MHT decreased significantly after the turn of the century. It has increased since 2017, mainly in the age groups close to menopause. The increase in incidence preceded the prevalence and seems to be a more sensitive measure than prevalence or DDD for detecting early changes in prescription trends of MHT. A run-in period of 18 months seems to be reliable to identify incident users in the ages close to menopause.

Place, publisher, year, edition, pages
WILEY , 2023. Vol. 102, no Suppl. 1, p. 70-70
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:oru:diva-112581ISI: 001183994700152OAI: oai:DiVA.org:oru-112581DiVA, id: diva2:1846735
Conference
42nd Nordic Congress of Obstetrics and Gynecology (NFOG 2023), Trondheim, Norway, August 27-30, 2023
Available from: 2024-03-25 Created: 2024-03-25 Last updated: 2024-05-27Bibliographically approved

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Brynhildsen, Jan

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