oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Full-field electroretinography and marked variability in clinical phenotype of Alström syndrome
Show others and affiliations
2008 (English)In: Archives of ophthalmology (1960), ISSN 0003-9950, Vol. 126, no 1, 51-57 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: To characterize the clinical phenotype and to study the course of disease in patients with Alström syndrome, with an emphasis on retinal function assessed with full-field electroretinography (ERG). METHODS: Three age- and sex-matched patients with Alström syndrome were selected from our retinitis pigmentosa register for repeated ophthalmologic examinations that included tests for color vision and visual fields using Goldmann perimetry and for repeated assessment of full-field ERGs. RESULTS: Electroretinography demonstrated cone-rod degeneration in all 3 patients. A concomitant impairment of color vision and visual fields was also observed as well as marked variation in retinal function and in disease severity. CONCLUSIONS: Full-field ERGs confirmed that Alström syndrome is associated with a cone-rod type of retinal degeneration. In this study, we have shown a striking variability in retinal function and disease onset and severity, which has, to our knowledge, not been described previously in Alström syndrome.

Place, publisher, year, edition, pages
Chicago: American medical association , 2008. Vol. 126, no 1, 51-57 p.
National Category
Medical and Health Sciences Ophthalmology
Research subject
Medicine
Identifiers
URN: urn:nbn:se:oru:diva-6953DOI: 10.1001/archophthalmol.2007.28PubMedID: 18195218OAI: oai:DiVA.org:oru-6953DiVA: diva2:219448
Available from: 2009-05-27 Created: 2009-05-27 Last updated: 2016-12-16Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Möller, Claes
By organisation
School of Health and Medical Sciences
In the same journal
Archives of ophthalmology (1960)
Medical and Health SciencesOphthalmology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 249 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf