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Changes in mini mental state examination score after stroke: lacunar infarction predicts cognitive decline
Örebro University, Department of Clinical Medicine.
2006 (English)In: European Journal of Neurology, ISSN 1351-5101, E-ISSN 1468-1331, Vol. 13, no 5, 491-495 p.Article in journal (Refereed) Published
Abstract [en]

Stroke and cognitive impairment are inter-related. The purpose of this study was to show the natural evolution of cognitive performance during the first year after a stroke, and to show which factors that predict cognitive decline. Subjects were patients with a first-ever stroke who were treated in a stroke unit. A total of 160 patients were included. At baseline patients were evaluated with regard to stroke type, stroke severity, pre-stroke dementia and other risk factors. Mini Mental State Examinations (MMSE) were performed after 1 week and after 1 year. Patients had a median increase of 1 point (range -8 to +9) on the MMSE. Thirty-two pre cent of the patients deteriorated, 13% were unchanged, and 55% improved. Lacunar infarction (LI) and left-sided stroke were associated with a failure to exhibit improvement. Patients with LI had an average decline of 1.7 points, whilst patients with other stroke types had an average increase of 1.8 points. Most stroke survivors improve cognitively during the first year after the event. The outcome for LI patients is worse, which suggests that LI may serve as a marker for concomitant processes that cause cognitive decline.

Place, publisher, year, edition, pages
2006. Vol. 13, no 5, 491-495 p.
National Category
Medical and Health Sciences Geriatrics Neurology
Research subject
Geriatrics; Neurology
Identifiers
URN: urn:nbn:se:oru:diva-11101DOI: 10.1111/j.1468-1331.2006.01299.xPubMedID: 16722974OAI: oai:DiVA.org:oru-11101DiVA: diva2:324917
Available from: 2010-06-16 Created: 2010-06-16 Last updated: 2017-12-12Bibliographically approved

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Appelros, Peter

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