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Influence of more than six sternal fixation wires on the incidence of deep sternal wound infection
Örebro University, Department of Clinical Medicine.ORCID iD: 0000-0001-5939-2932
Örebro University, Department of Clinical Medicine.ORCID iD: 0000-0003-2625-4597
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2006 (English)In: The thoracic and cardiovascular surgeon, ISSN 0171-6425, E-ISSN 1439-1902, Vol. 54, no 7, p. 468-473Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The aim of the present study was to examine the influence of the number of sternal fixation wires used on deep sternal wound infection rate and to analyze any possible interaction between this and local collagen-gentamicin prophylaxis evaluated in a previous trial. METHODS: The number of sternal fixation wires in all patients from one of two participating centers was counted. The patients were categorized according to six or fewer (standard technique, ST group) vs. seven or more wires (extra wires, XW group). RESULTS: The incidence of deep sternal wound infection was 4.2 % in the ST group and 0.4 % in the XW group ( P = 0.001). An analysis of the effect of local gentamicin, excluding the ST group from the analysis, showed an approximately 70 % reduction in sternal wound infection for all depths. CONCLUSION: This study supports the theory that additional fixation wires at the lower sternum actually reduce the incidence of deep wound infections. We suggest that a rigid sternal fixation is required to achieve the full benefit of local collagen-gentamicin prophylaxis.

Place, publisher, year, edition, pages
2006. Vol. 54, no 7, p. 468-473
National Category
Medical and Health Sciences Surgery
Research subject
Surgery esp. Thoracic and Cardivascular Surgery
Identifiers
URN: urn:nbn:se:oru:diva-11121DOI: 10.1055/s-2006-924437PubMedID: 17089314OAI: oai:DiVA.org:oru-11121DiVA, id: diva2:324947
Available from: 2010-06-16 Created: 2010-06-16 Last updated: 2017-12-12Bibliographically approved

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Söderquist, BoKällman, J.

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