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Helicobacter pylori adhesion to carbohydrates
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2006 (English)In: Methods in Enzymology, ISSN 0076-6879, E-ISSN 1557-7988, Vol. 417, 293-339 p.Article in journal (Refereed) Published
Abstract [en]

Adherence of bacterial pathogens to host tissues contributes to colonization and virulence and typically involves specific interactions between bacterial proteins called adhesins and cognate oligosaccharide (glycan) or protein motifs in the host that are used as receptors. A given pathogen may have multiple adhesins, each specific for a different set of receptors and, potentially, with different roles in infection and disease. This chapter provides strategies for identifying and analyzing host glycan receptors and the bacterial adhesins that exploit them as receptors, with particular reference to adherence of the gastric pathogen Helicobacter pylori.

Place, publisher, year, edition, pages
2006. Vol. 417, 293-339 p.
National Category
Medical and Health Sciences Microbiology in the medical area
Research subject
Medicine
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URN: urn:nbn:se:oru:diva-12057DOI: 10.1016/S0076-6879(06)17020-2PubMedID: 17132512OAI: oai:DiVA.org:oru-12057DiVA: diva2:355132
Available from: 2010-10-05 Created: 2010-10-05 Last updated: 2017-12-12Bibliographically approved

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Unemo, Magnus

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