oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The biology of satellite cells and telomeres in human skeletal muscle: effects of aging and physical activity
Örebro University, School of Health and Medical Sciences. (Muscle & Exercise Physiology Research Group , RISPA)ORCID iD: 0000-0002-9831-0896
Örebro University, School of Health and Medical Sciences. (Muscle & Exercise Physiology Research Group , RISPA)ORCID iD: 0000-0002-8071-4745
2010 (English)In: Scandinavian Journal of Medicine and Science in Sports, ISSN 0905-7188, E-ISSN 1600-0838, Vol. 20, no 1, p. 39-48Article, review/survey (Refereed) Published
Abstract [en]

The decline in the neuromuscular function affects the physical performance and is a threat for independent living in later life. The age-related decrease in muscle satellite cells observed by the age of 70 can be specific to type II fibers in some muscles. Several studies have shown that different forms of exercise induce the expansion of satellite cell pool in human skeletal muscle of young and elderly. Exercise is a powerful non-pharmacological tool inducing the renewal of the satellite cell pool in skeletal muscles. Skeletal muscle is not a stable tissue as satellite cells are constantly recruited during normal daily activities. Satellite cells and the length of telomeres are important in the context of muscle regeneration. It is likely that the regulation of telomeres in vitro cannot fully mimic the behavior of telomeres in human tissues. New insights suggest that telomeres in skeletal muscle are dynamic structures under the influence of their environment. When satellite cells are heavily recruited for regenerative events as in the skeletal muscle of athletes, telomere length has been found to be either dramatically shortened or maintained and even longer than in non-trained individuals. This suggests the existence of mechanisms allowing the control of telomere length in vivo.

Place, publisher, year, edition, pages
2010. Vol. 20, no 1, p. 39-48
Keyword [en]
aging, exercise, human, satellite cell, regeneration, telomere, muscle, leukocyte
National Category
Sport and Fitness Sciences
Research subject
Sports Science
Identifiers
URN: urn:nbn:se:oru:diva-13030DOI: 10.1111/j.1600-0838.2009.00966.xISI: 000273823400006OAI: oai:DiVA.org:oru-13030DiVA: diva2:382740
Available from: 2011-01-03 Created: 2011-01-03 Last updated: 2017-12-11Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text

Authority records BETA

Kadi, FawziPonsot, Elodie

Search in DiVA

By author/editor
Kadi, FawziPonsot, Elodie
By organisation
School of Health and Medical Sciences
In the same journal
Scandinavian Journal of Medicine and Science in Sports
Sport and Fitness Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 295 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf