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Effects of adenosine A(2A) and A(2B) receptor activation on signaling pathways and cytokine production in human uroepithelial cells
Örebro University, School of Health and Medical Sciences.
2010 (English)In: Pharmacology, ISSN 0031-7012, E-ISSN 1423-0313, Vol. 86, no 3, p. 129-137Article in journal (Refereed) Published
Abstract [en]

our data identified differences in signaling pathways evoked by adenosine A(2A) and A(2B) receptor activation. Activation of the adenosine A(2A) receptor inhibited STAT3 and ERK 1/2 phosphorylation, while the cAMP-CREB pathway was induced by adenosine A(2B) receptor activation. No anti- or proinflammatory effects were found for uroepithelial adenosine A(2A) or A(2B) receptors.

Place, publisher, year, edition, pages
2010. Vol. 86, no 3, p. 129-137
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Medical and Health Sciences
Research subject
Biomedicine
Identifiers
URN: urn:nbn:se:oru:diva-13461DOI: 10.1159/000317068PubMedID: 20689344OAI: oai:DiVA.org:oru-13461DiVA: diva2:386070
Available from: 2011-01-12 Created: 2011-01-12 Last updated: 2017-12-11Bibliographically approved

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Persson, Katarina

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