Microscopic colitis: current status, present and future challenges statements of the European microscopic colitis groupShow others and affiliations
2012 (English)In: Journal of Crohn's & Colitis, ISSN 1873-9946, E-ISSN 1876-4479, Vol. 6, no 9, p. 932-945Article in journal (Refereed) Published
Abstract [en]
Microscopic colitis (MC) is an inflammatory bowel disease presenting with chronic, non-bloody watery diarrhoea and few or no endoscopic abnormalities. The histological examination reveals mainly two subtypes of MC, lymphocytic or collagenous colitis. Despite the fact that the incidence in MC has been rising over the last decades, research has been sparse and our knowledge about MC remains limited. Specialists in the field have initiated the European Microscopic Colitis Group (EMCG) with the primary goal to create awareness on MC. The EMCG is furthermore a forum with the intention to promote clinical and basic research. In this article statements and comments are given that all members of the EMCG have considered being of importance for a better understanding of MC. The paper focuses on the newest updates in epidemiology, symptoms and diagnostic criteria, pathophysiology and highlights some unsolved problems. Moreover, a new treatment algorithm is proposed on the basis of new evidence from well-designed, randomized control trials.
Place, publisher, year, edition, pages
Amsterdam, Netherlands: Elsevier, 2012. Vol. 6, no 9, p. 932-945
National Category
Medical and Health Sciences Gastroenterology and Hepatology
Research subject
Medicine
Identifiers
URN: urn:nbn:se:oru:diva-24222DOI: 10.1016/j.crohns.2012.05.014ISI: 000309990400009PubMedID: 22704658Scopus ID: 2-s2.0-84865736716OAI: oai:DiVA.org:oru-24222DiVA, id: diva2:542844
Funder
AstraZeneca
Note
Funding Agencies:
Tillots Pharma
Falk Pharma
Ferring
Falk Foundation, Germany
MSD
MEDA, Sweden
Note: Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas (CIBEREHD)
2012-08-032012-08-032025-02-11Bibliographically approved