oru.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Incidence and management of Streptococcus pneumoniae as a causative agent of meningitis
Örebro University, School of Science and Technology.
2013 (English)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Pneumococcal meningitis is a bacterial infectious disease with a high yearly rate of morbidity and mortality around the world. Pneumococcal meningitis is mostly death threatening to infants older than two months, adolescents and adults. Streptococcus pneumoniae is the causative agent of pneumococcal meningitis which produces inflammation of the meninges. S. pneumoniae adheres to and colonize the epithelial cells of the nasopharynx which allows the bacterial pathogen to enter the blood stream and reach the brain cerebrospinal fluid (CSF) and causes brain injury. The role of one of the putative virulence factor, pneumolysin is important for disease progression. Neurological disorders and a range of complications and symptoms vary according to the age of patient. Different clinical diagnostics are used to identify bacterial pathogens. Epidemiological data shows prevalence of bacterial meningitis in USA, Europe, Mediterranean region and in the African meningitis belt. The pneumococcal meningitis was one of the most deadly diseases before the production of antibiotics in the 1930s and 1940s. The treatment of pneumococcal meningitis depends on the mode of action of different types of antibiotics. Most cases of pneumococcal meningitis are in children under two years of age, elderly and in adults and correlate to various risk factors. The transmission of pneumococcal meningitis, prevention from the spread of pneumococcal meningitis, antibiotics treatment of pneumococcal meningitis, use of vaccines and the future research for the development of new treatments to eradicate pneumococcal meningitis is discussed in this review.

Place, publisher, year, edition, pages
2013.
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:oru:diva-28599ISRN: ORU-NAT/BIO-AG-2013/0001--SEOAI: oai:DiVA.org:oru-28599DiVA, id: diva2:614921
Subject / course
Biology
Supervisors
Examiners
Available from: 2013-04-29 Created: 2013-04-08 Last updated: 2017-10-17Bibliographically approved

Open Access in DiVA

No full text in DiVA

By organisation
School of Science and Technology
Biological Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 60 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf