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Hand eczema and health-related quality of life: a comparison of EQ-5D and the Dermatology Life Quality Index (DLQI) in relation to the hand eczema extent score (HEES)
Örebro University, School of Medicine, Örebro University, Sweden. Department of Dermatology, Örebro University Hospital, Region Örebro County, Örebro, Sweden.
Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden.
Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Centre for Clinical Research Sörmland, Eskilstuna, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
2013 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 69, no 3, p. 138-143Article in journal (Refereed) Published
Abstract [en]

Background: Health-related quality of life (HRQoL) is associated with the extent and severity of hand eczema. We still lack a consensus about which HRQoL instrument to use as the standard, and how to measure the extent and severity of hand eczema.

Objectives: To compare the Dermatology Life Quality Index (DLQI) with EQ-5D (a standardized instrument for use as a measure of health outcome), and to evaluate how the Hand Eczema Extent Score (HEES) relates to these instruments.

Methods: Ninety-three patients (61 females) were included. The HEES was recorded by a dermatologist, and the DLQI and EQ-5D by the patients. The results were analysed with factor analysis and non-parametric statistics.

Results: The DLQI and EQ-5D showed decreased HRQoL. Using factor analysis, we could not establish an association between the DLQI and EQ-5D. There were, however, correlations between the DLQI and the HEES (0.31), the EQ(index) and the HEES (-0.32), the DLQI and the EQ(VAS) (-0.62), and the DLQI and the EQ(index) (-0.67) (the EQ(VAS) and the EQ(index) are calculated from EQ-5D).

Conclusions: We could not link factors in the DLQI to EQ-5D, which has previously been done for SF-36 (Short Form 36). On the basis of this, we cannot recommend EQ-5D over SF-36 for hand eczema studies. The DLQI correlates with the EQ(VAS) and the EQ(index), and can probably be used as an approximation for EQ-5D. Our findings with the HEES are interesting, as it can be used by patients.

Place, publisher, year, edition, pages
Hoboken, USA: Wiley-Blackwell, 2013. Vol. 69, no 3, p. 138-143
Keywords [en]
DLQI, EQ-5D, hand eczema, HEES, quality of life
National Category
Dermatology and Venereal Diseases
Research subject
Medicine
Identifiers
URN: urn:nbn:se:oru:diva-30720DOI: 10.1111/cod.12067ISI: 000323154700002PubMedID: 23948032Scopus ID: 2-s2.0-84882370082OAI: oai:DiVA.org:oru-30720DiVA, id: diva2:647276
Note

Funding Agencies:

Swedish Asthma and Allergy Research Foundation 

Finsen-Welander Foundation 

FoU centre Sörmland 

Available from: 2013-09-11 Created: 2013-09-06 Last updated: 2018-05-21Bibliographically approved

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Lindberg, Magnus

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