In this paper we investigate appropriate cross-border collaboration areas, by introducing the concept eHealth governance area (eHgov area). Our basic principles lie in the perspective of information infrastructures and IT governance, and investigate areas of collaboration in health care. The empirical data originates from a study in Swedish health care. Our conclusion from this study implies that the basis in workflow processes is the key issue to reach appropriate cross-border collaboration in health care. In the paper we identify 9 areas for collaboration; laboratory test diagnosis, dental care, perioperative care, pregnancy and obstetric care, emergency medical care, imaging and functional diagnosis, prescription, patient administration, and medical records.