oru.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Homocystinuria and oral health. A report of 14 cases
Department of Orthodontics, Eskilstuna, Sweden; Department of Orthodontics, Postgraduate Dental Education Centre, Örebro, Sweden .
Örebro University, School of Health and Medical Sciences, Örebro University, Sweden. Postgraduate Dental Education Centre, Örebro, Sweden; Department of Behavioural and Community Dentistry, Institution of Odontology, University of Gothenburg, Gothenburg, Sweden.
2012 (English)In: Swedish Dental Journal, ISSN 0347-9994, Vol. 36, no 2, p. 101-108Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to explore the oral health in Swedish individuals with the diagnosis of homozygote cystathionine beta synthase-deficient homocystinuria (HC), a rare disorder of amino acid metabolism affecting connective tissue, in which the phenotypic abnormalities include dislocation of the optic lens, skeletal abnormalities, thromboembolic events, and sometimes mental retardation. Further aims were to evaluate the oral findings against previous oral observations in a medical case report, such as high narrow palate, mandibular prognathia, crowding and early eruption of teeth. Every hospital in Sweden was contacted, with the inquiry of patients with diagnosis of HC, which resulted in 14 individuals participating in oral clinical examination. The oral findings evaluated against previous medical case reports showed to be partly in accordance with previous observations. Dental health showed to be compromised in a majority of cases. Together with the fact that methionine restriction (low-protein diet) is involved in the treatment of the condition and might result in a diet high in sugars,this points out the role of regular dental checkups and preventive oral care for individuals suffering from HC. In addition, short dental roots were a finding not previously reported in the literature. All the studied cases had central maxillary incisors with short roots, when compared to reference values used.

Place, publisher, year, edition, pages
Stockholm: Swedish Dental Journal , 2012. Vol. 36, no 2, p. 101-108
Keywords [en]
Oral health, amino acid metabolism, extracellular matrix, connective tissue, oral manifestations
National Category
Medical and Health Sciences Dentistry
Identifiers
URN: urn:nbn:se:oru:diva-32937ISI: 000327048700005PubMedID: 22876397Scopus ID: 2-s2.0-84863846502OAI: oai:DiVA.org:oru-32937DiVA, id: diva2:683395
Note

Funding Agency: Public Dental Service; Sormland County Council research and development committee; Örebro County Council

Available from: 2014-01-03 Created: 2014-01-03 Last updated: 2018-05-13Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

PubMedScopusTidskrift

Authority records BETA

Björksved, MargithaArnrup, Kristina

Search in DiVA

By author/editor
Björksved, MargithaArnrup, Kristina
By organisation
School of Health and Medical Sciences, Örebro University, Sweden
In the same journal
Swedish Dental Journal
Medical and Health SciencesDentistry

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 49 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf