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Quality of life and persisting symptoms after oesophageal cancer surgery
Unit of Esophageal and Gastric Research, Department of Molecular Medicine and Surgery P9:03, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Unit of Esophageal and Gastric Research, Department of Molecular Medicine and Surgery P9:03, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Unit of Esophageal and Gastric Research, Department of Molecular Medicine and Surgery P9:03, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
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2006 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 42, no 10, 1407-1414 p.Article in journal (Refereed) Published
Abstract [en]

To assess quality of life (QoL) and symptoms after oesophageal cancer surgery, a prospective nationwide population-based study was conducted in 2001-2005, including most surgically treated oesophageal cancer patients in Sweden. Six months postoperatively patients responded to an EORTC quality of life core questionnaire (QLQ C-30) with an oesophageal-specific module (OES-18). Mean scores were calculated. Mann-Whitney test was used for group comparisons. Among 282 patients, QoL was considerably reduced compared to a reference general population (P < 0.001), and functioning scales were similarly negatively affected; particularly role (P < 0.001) and social (P < 0.001) functions. Younger patients scored worse than older. No gender differences were found. Dominating general symptoms included fatigue, appetite loss, diarrhoea, and dyspnoea, each significantly more pronounced than the general population (P < 0.001). Eating problems, cough, reflux, and oesophageal pain were common oesophageal-specific symptoms. Thus, patients who undergo oesophageal cancer resection suffer greatly from reduced QoL and several general and oesophageal-specific symptoms six months postoperatively. (c) 2006 Elsevier Ltd. All rights reserved.

Place, publisher, year, edition, pages
2006. Vol. 42, no 10, 1407-1414 p.
Keyword [en]
Questionnaires, EORTC, QLQ-C 30, QLQ-OES 18, Oesophagectomy, Cardia cancer
National Category
Nursing
Research subject
Nursing Science
Identifiers
URN: urn:nbn:se:oru:diva-36354DOI: 10.1016/j.ejca.2006.02.005ISI: 000238969600025PubMedID: 16737812Scopus ID: 2-s2.0-33745179241OAI: oai:DiVA.org:oru-36354DiVA: diva2:745735
Available from: 2014-09-11 Created: 2014-09-02 Last updated: 2017-10-17Bibliographically approved

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