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Kidney Cancer
Channing Laboratory, Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
Örebro University, School of Medicine, Örebro University, Sweden. Department of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; and Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
2008 (English)In: Textbook of cancer epidemiology / [ed] Hans-Olov Adam, David J. Hunter, Dimitrios Trichopoulos, Oxford, United Kingdom: Oxford University Press , 2008, 2nd ed.Chapter in book (Other academic)
Abstract [en]

Cigarette smoking and obesity may account for approximately 40% of cases in high-incidence countries. Continued research in kidney cancer is needed since nearly 50% of the patients die within five years after diagnosis. With the aim of prevention, the continued search for environmental causes should take into account the fact that kidney cancer consists of different types with specific genetic molecular characteristics. In some cases, these genetic alterations have been purportedly associated with specific exposures. Furthermore, genetic polymorphisms may have a modulating effect on metabolic activation and detoxification enzymes. Thus, better understanding of the genetic and molecular processes involved in kidney cancer may help with the analyzing exposure associations that are important in both its initiation and progression.

Place, publisher, year, edition, pages
Oxford, United Kingdom: Oxford University Press , 2008, 2nd ed..
Series
Monographs in epidemiology and biostatistics, ISSN 0740-0845
Keywords [en]
Tobacco, obesity, genetic polymorphisms, hypertension, diet
National Category
Medical and Health Sciences Cancer and Oncology
Identifiers
URN: urn:nbn:se:oru:diva-40573DOI: 10.1093/acprof:oso/9780195311174.003.0023ISBN: 9780195311174 (print)OAI: oai:DiVA.org:oru-40573DiVA, id: diva2:777594
Available from: 2015-01-08 Created: 2015-01-08 Last updated: 2017-10-17Bibliographically approved

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Lindblad, Per

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
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  • modern-language-association-8th-edition
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  • fi-FI
  • nn-NO
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  • Other locale
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